CoA in Health and Disease
Overview
Chemistry
Molecular Biology
Authors
Affiliations
Coenzyme A (CoA) and its thioester derivatives are crucial components of numerous biosynthetic and degradative pathways of the cellular metabolism (including fatty acid synthesis and oxidation, the Krebs cycle, ketogenesis, cholesterol and acetylcholine biosynthesis, amino acid degradation, and neurotransmitter biosynthesis), post-translational modifications of proteins, and the regulation of gene expression [...].
Shao Y, Hu J, Yan K, Zheng K, Sha W, Wang J Cell Mol Life Sci. 2025; 82(1):84.
PMID: 39985665 PMC: 11846818. DOI: 10.1007/s00018-025-05576-1.
Bai J, Yu B, Li C, Cheng H, Guan Y, Ren Z Adv Healthc Mater. 2023; 13(3):e2302128.
PMID: 37922434 PMC: 11468562. DOI: 10.1002/adhm.202302128.