A Frameshift in Time

Overview

Journal Elife

Specialty Biology

Date 2022 Apr 11

PMID 35404784

Authors

Martina M Yordanova

Pavel V Baranov

Affiliations

Soon will be listed here.

Abstract

The efficiency with which ribosomes shift reading frames when decoding viral RNA may change over the course of an infection.

Citing Articles

Ribosome profiling reveals downregulation of UMP biosynthesis as the major early response to phage infection.

OConnor P, Mahony J, Casey E, Baranov P, Van Sinderen D, Yordanova M Microbiol Spectr. 2024; 12(4):e0398923.

PMID: 38451091 PMC: 10986495. DOI: 10.1128/spectrum.03989-23.

Nontriplet feature of genetic code in ciliates is a result of neutral evolution.

Gaydukova S, Moldovan M, Vallesi A, Heaphy S, Atkins J, Gelfand M Proc Natl Acad Sci U S A. 2023; 120(22):e2221683120.

PMID: 37216548 PMC: 10235951. DOI: 10.1073/pnas.2221683120.

Evolution of coronavirus frameshifting elements: Competing stem networks explain conservation and variability.

Yan S, Zhu Q, Hohl J, Dong A, Schlick T Proc Natl Acad Sci U S A. 2023; 120(20):e2221324120.

PMID: 37155888 PMC: 10193956. DOI: 10.1073/pnas.2221324120.

References

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Riegger R, Caliskan N . Thinking Outside the Frame: Impacting Genomes Capacity by Programmed Ribosomal Frameshifting. Front Mol Biosci. 2022; 9:842261. PMC: 8915115. DOI: 10.3389/fmolb.2022.842261. View

Atkins J, Loughran G, Bhatt P, Firth A, Baranov P . Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use. Nucleic Acids Res. 2016; 44(15):7007-78. PMC: 5009743. DOI: 10.1093/nar/gkw530. View