Genomic Sequencing in Oncology: Considerations for Integration in Routine Cancer Care

Overview

Journal Eur J Cancer Care (Engl)

Publisher Wiley

Specialties Nursing
Oncology

Date 2022 Apr 6

PMID 35383404

Authors

Belinda Rahman

Alastair Lamb

Andrew Protheroe

Ketan Shah

Joyce Solomons

Jonathan Williams

Elizabeth Ormondroyd

Affiliations

Soon will be listed here.

Citing Articles

Co-design of patient information leaflets for germline predisposition to cancer: recommendations for clinical practice from the UK Cancer Genetics Group (UKCGG), Cancer Research UK (CRUK) funded CanGene-CanVar Programme and the Association of....

Kohut K, Speight B, Young J, Way R, Wiggins J, Monje-Garcia L J Med Genet. 2023; 61(2):142-149.

PMID: 38050080 PMC: 11881048. DOI: 10.1136/jmg-2023-109440.

Genomic sequencing in oncology: Considerations for integration in routine cancer care.

Rahman B, Lamb A, Protheroe A, Shah K, Solomons J, Williams J Eur J Cancer Care (Engl). 2022; 31(3):e13584.

PMID: 35383404 PMC: 9285419. DOI: 10.1111/ecc.13584.

References

Vassy J, Korf B, Green R . How to know when physicians are ready for genomic medicine. Sci Transl Med. 2015; 7(287):287fs19. PMC: 4519005. DOI: 10.1126/scitranslmed.aaa2401. View

Johnson L, Valdez J, Quinn E, Sykes A, McGee R, Nuccio R . Integrating next-generation sequencing into pediatric oncology practice: An assessment of physician confidence and understanding of clinical genomics. Cancer. 2017; 123(12):2352-2359. PMC: 5710798. DOI: 10.1002/cncr.30581. View

Wain K, Azzariti D, Goldstein J, Johnson A, Krautscheid P, Lepore B . Variant interpretation is a component of clinical practice among genetic counselors in multiple specialties. Genet Med. 2019; 22(4):785-792. PMC: 7127982. DOI: 10.1038/s41436-019-0705-9. View

Pearce C, Goettke E, Hallowell N, McCormack P, Flinter F, McKevitt C . Delivering genomic medicine in the United Kingdom National Health Service: a systematic review and narrative synthesis. Genet Med. 2019; 21(12):2667-2675. DOI: 10.1038/s41436-019-0579-x. View

Chow-White P, Ha D, Laskin J . Knowledge, attitudes, and values among physicians working with clinical genomics: a survey of medical oncologists. Hum Resour Health. 2017; 15(1):42. PMC: 5488429. DOI: 10.1186/s12960-017-0218-z. View

Zebrowski A, Ellis D, Barg F, Sperber N, Bernhardt B, Denny J . Qualitative study of system-level factors related to genomic implementation. Genet Med. 2018; 21(7):1534-1540. PMC: 6533158. DOI: 10.1038/s41436-018-0378-9. View

Raghavan S, Vassy J . Do physicians think genomic medicine will be useful for patient care?. Per Med. 2015; 11(4):424-433. PMC: 4494677. DOI: 10.2217/pme.14.25. View

de Moor J, Gray S, Mitchell S, Klabunde C, Freedman A . Oncologist Confidence in Genomic Testing and Implications for Using Multimarker Tumor Panel Tests in Practice. JCO Precis Oncol. 2020; 4. PMC: 7446310. DOI: 10.1200/PO.19.00338. View

Patch C, Middleton A . Genetic counselling in the era of genomic medicine. Br Med Bull. 2018; 126(1):27-36. PMC: 5998955. DOI: 10.1093/bmb/ldy008. View

10.

Patch C, Middleton A . Point of View: An evolution from genetic counselling to genomic counselling. Eur J Med Genet. 2019; 62(5):288-289. DOI: 10.1016/j.ejmg.2019.04.010. View

11.

van de Haar J, Hoes L, Voest E . Advancing molecular tumour boards: highly needed to maximise the impact of precision medicine. ESMO Open. 2019; 4(2):e000516. PMC: 6555597. DOI: 10.1136/esmoopen-2019-000516. View

12.

Kirk M, Tonkin E, Skirton H . An iterative consensus-building approach to revising a genetics/genomics competency framework for nurse education in the UK. J Adv Nurs. 2013; 70(2):405-20. PMC: 3907026. DOI: 10.1111/jan.12207. View

13.

Gray S, Hicks-Courant K, Cronin A, Rollins B, Weeks J . Physicians' attitudes about multiplex tumor genomic testing. J Clin Oncol. 2014; 32(13):1317-23. PMC: 3992721. DOI: 10.1200/JCO.2013.52.4298. View

14.

Berger M, Mardis E . The emerging clinical relevance of genomics in cancer medicine. Nat Rev Clin Oncol. 2018; 15(6):353-365. PMC: 6658089. DOI: 10.1038/s41571-018-0002-6. View

15.

Wright H, Zhao L, Birks M, Mills J . Nurses' competence in genetics: An integrative review. Nurs Health Sci. 2018; 20(2):142-153. DOI: 10.1111/nhs.12401. View

16.

Vetsch J, Wakefield C, Techakesari P, Warby M, Ziegler D, OBrien T . Healthcare professionals' attitudes toward cancer precision medicine: A systematic review. Semin Oncol. 2019; 46(3):291-303. DOI: 10.1053/j.seminoncol.2019.05.001. View

17.

Percival N, George A, Gyertson J, Hamill M, Fernandes A, Davies E . The integration of BRCA testing into oncology clinics. Br J Nurs. 2016; 25(12):690-4. PMC: 5993185. DOI: 10.12968/bjon.2016.25.12.690. View

18.

Gomez-Lopez G, Dopazo J, Cigudosa J, Valencia A, Al-Shahrour F . Precision medicine needs pioneering clinical bioinformaticians. Brief Bioinform. 2017; 20(3):752-766. DOI: 10.1093/bib/bbx144. View

19.

Gingras I, Sonnenblick A, de Azambuja E, Paesmans M, Delaloge S, Aftimos P . The current use and attitudes towards tumor genome sequencing in breast cancer. Sci Rep. 2016; 6:22517. PMC: 4773754. DOI: 10.1038/srep22517. View

20.

Bancroft E, Kohut K, Eeles R . The New Genomics Era: Integration of genomics into mainstream oncology and implications for psycho-oncological care. Psychooncology. 2020; 29(3):453-460. DOI: 10.1002/pon.5331. View