» Articles » PMID: 35371575

"The Baltic Sea Germ": A Case Report of Necrotizing Fasciitis Following Vibrio Vulnificus Infection

Overview
Journal Case Rep Orthop
Publisher Wiley
Specialty Orthopedics
Date 2022 Apr 4
PMID 35371575
Authors
Affiliations
Soon will be listed here.
Abstract

Reported is an 80-year-old patient with septic shock from necrotizing fasciitis secondary to a Vibrio vulnificus (Vv) infection. The patient reports having been swimming in the Baltic Sea after a minor trauma to the left leg. Emergency superficial necrosectomy followed by intensive medical therapy was performed. Antibiotic therapy was initiated with a third-generation cephalosporin and a tetracycline. Vv was detected in the intraoperative microbiological smears. Instead of a leg amputation and a flap, due to the patient's age, a split skin covering to consolidate the wound was performed. Vv is a gram-negative rod bacterium of the genus Vibrio. Vv occurs in warm, low-salinity seawater (brackish water). In Germany, Vv occurs primarily in river mouths of the low-salinity Baltic Sea. Infections by Vv can occur through open wounds or by eating raw infected seafood, especially oysters. Infection via wounds often take a fulminant lethal course. Patients with chronic diseases, weakened immune system, and open wounds are particularly at risk. Infections with Vv are rare, but occur worldwide. Global warming is expected to spread Vv as water temperature increases and the dilution effect of sea level rise further decreases ocean salinity, and natural disasters promote the spread of Vv.

Citing Articles

Function of Gene Response to Infection and LPS Stimulation in the Half-Smooth Tongue Sole ().

Han T, Liu Y, Li M, Zhang Y, He Z, Ren Y Int J Mol Sci. 2025; 26(5).

PMID: 40076623 PMC: 11900322. DOI: 10.3390/ijms26051999.


Pathogenetic detection, retrospective and pathogenicity analysis of a fatal case of Vibrio vulnificus in Shenzhen, China.

Xu S, Wu J, Jin Y, Ji L, Zou X, Hu Q Gut Pathog. 2023; 15(1):57.

PMID: 38007445 PMC: 10675978. DOI: 10.1186/s13099-023-00580-x.


Impact of climate change on waterborne infections and intoxications.

Dupke S, Buchholz U, Fastner J, Forster C, Frank C, Lewin A J Health Monit. 2023; 8(Suppl 3):62-77.

PMID: 37342430 PMC: 10278370. DOI: 10.25646/11402.

References
1.
Noori V, Trehan K, Savetamal A, Carter D . New onset squamous cell carcinoma in previous split-thickness skin graft donor site. Int J Surg. 2018; 52:16-19. DOI: 10.1016/j.ijsu.2018.01.047. View

2.
Liu J, Lee I, Tang H, Ko W, Lee H, Liu Y . Prognostic factors and antibiotics in Vibrio vulnificus septicemia. Arch Intern Med. 2006; 166(19):2117-23. DOI: 10.1001/archinte.166.19.2117. View

3.
Jones M, Oliver J . Vibrio vulnificus: disease and pathogenesis. Infect Immun. 2009; 77(5):1723-33. PMC: 2681776. DOI: 10.1128/IAI.01046-08. View

4.
Frank C, Littman M, Alpers K, Hallauer J . Vibrio vulnificus wound infections after contact with the Baltic Sea, Germany. Euro Surveill. 2006; 11(8):E060817.1. DOI: 10.2807/esw.11.33.03024-en. View

5.
Horre R, Becker S, Marklein G, Shimada T, Stephan R, Steuer K . Necrotizing fasciitis caused by Vibrio vulnificus: first published infection acquired in Turkey is the second time a strain is isolated in Germany. Infection. 1998; 26(6):399-401. DOI: 10.1007/BF02770844. View