Creating a User-Friendly and Open-Access Gene Expression Database for Comparing Embryonic Development and Regeneration in Nematostella Vectensis
Overview
Overview
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
Abstract
The sea anemone Nematostella vectensis has emerged as a powerful research model to understand at the gene regulatory network level, to what extend regeneration recapitulates embryonic development. Such comparison involves massive transcriptomic analysis, a routine approach for identifying differential gene expression. Here we present a workflow to build a user-friendly, mineable, and open-access database providing access to the scientific community to various RNAseq datasets.
References
1.
Rentzsch F, Fritzenwanker J, Scholz C, Technau U
. FGF signalling controls formation of the apical sensory organ in the cnidarian Nematostella vectensis. Development. 2008; 135(10):1761-9.
DOI: 10.1242/dev.020784.
View
2.
Putnam N, Srivastava M, Hellsten U, Dirks B, Chapman J, Salamov A
. Sea anemone genome reveals ancestral eumetazoan gene repertoire and genomic organization. Science. 2007; 317(5834):86-94.
DOI: 10.1126/science.1139158.
View
3.
Passamaneck Y, Martindale M
. Cell proliferation is necessary for the regeneration of oral structures in the anthozoan cnidarian Nematostella vectensis. BMC Dev Biol. 2012; 12:34.
PMC: 3553063.
DOI: 10.1186/1471-213X-12-34.
View
4.
Hand C, Uhlinger K
. The Culture, Sexual and Asexual Reproduction, and Growth of the Sea Anemone Nematostella vectensis. Biol Bull. 2018; 182(2):169-176.
DOI: 10.2307/1542110.
View
5.
Amiel A, Johnston H, Nedoncelle K, Warner J, Ferreira S, Rottinger E
. Characterization of Morphological and Cellular Events Underlying Oral Regeneration in the Sea Anemone, Nematostella vectensis. Int J Mol Sci. 2015; 16(12):28449-71.
PMC: 4691047.
DOI: 10.3390/ijms161226100.
View