» Articles » PMID: 35355611

Situs Inversus Totalis on F-FDG PET/CT: A Case Report and a Literature Review

Overview
Specialty General Medicine
Date 2022 Mar 31
PMID 35355611
Authors
Affiliations
Soon will be listed here.
Abstract

A 62-year-old female patient with pathologically confirmed left lung small cell neuroendocrine carcinoma. The patient was referred to our positron emission tomography (PET)/CT center to look for possible metastatic diseases. After fasting for 8 h, the fasting blood glucose level of the patient was 7.1 mmol/L. The patient was intravenously injected with a 6.42 mCi (238 MBq) F-fluorodeoxyglucose (FDG) imaging agent. After the patient rested for 1 h, we scanned the patient with SIEMENS Biograph mCT 64 PET/CT camera. In addition to lung tumors and lymph node diseases, abnormal tracer uptake in the patient's thyroid was also found. PET/CT also showed situs inversus totalis of the patient, including the dextrocardia, liver on the left side, stomach, and spleen on the right side of the patient's body. The identification of anatomical variations and abnormalities by PET/CT imaging is very important to develop the best treatment for lung cancer.

Citing Articles

Laparoscopy-assisted gastrectomy for advanced gastric cancer patients with situs inversus totalis: Two case reports and review of literature.

Liu H, Cai X, Lu Z, Xiong B, Peng C World J Gastrointest Surg. 2023; 15(9):2063-2073.

PMID: 37901733 PMC: 10600769. DOI: 10.4240/wjgs.v15.i9.2063.

References
1.
Rowe S, Pomper M . Molecular imaging in oncology: Current impact and future directions. CA Cancer J Clin. 2021; 72(4):333-352. PMC: 9189244. DOI: 10.3322/caac.21713. View

2.
Halac M, Mut S, Ylmaz S, Ergul N, Sonmezoglu K . Appearance of situs inversus totalis and polysplenia syndrome on FDG PET/CT. Clin Nucl Med. 2008; 33(2):142-3. DOI: 10.1097/RLU.0b013e31815ef836. View

3.
Rekhtman N . Lung neuroendocrine neoplasms: recent progress and persistent challenges. Mod Pathol. 2021; 35(Suppl 1):36-50. PMC: 8695375. DOI: 10.1038/s41379-021-00943-2. View

4.
Calabria F, Leporace M, Bagnato A . Situs Inversus Totalis and Cholangiocarcinoma of the Gallbladder Detected by 18F-FDG PET/CT. Clin Nucl Med. 2018; 43(6):439-440. DOI: 10.1097/RLU.0000000000002047. View

5.
Sackstein P, ONeil D, Neugut A, Chabot J, Fojo T . Epidemiologic trends in neuroendocrine tumors: An examination of incidence rates and survival of specific patient subgroups over the past 20 years. Semin Oncol. 2018; 45(4):249-258. DOI: 10.1053/j.seminoncol.2018.07.001. View