Macrolide Resistance in Mycoplasma Pneumoniae, Midwestern United States, 2014 to 2021

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 2022 Mar 21

PMID 35311520

Authors

Tanner E Rothstein

Scott A Cunningham

Rachelle A Rieke

Jill M Mainella

Melissa M Mutchler

Robin Patel

Affiliations

Soon will be listed here.

Abstract

The epidemiology of macrolide resistance in () in the United States is incompletely described. Using a PCR assay targeting common mutations associated with macrolide resistance in M. pneumoniae (23S rRNA gene, A2063G/A2064G), the frequency of macrolide resistance was estimated to be 10% based on analysis of 114 samples tested from January 2014 to September 2021 at Mayo Clinic Laboratories. Seasonality data showed the highest rates of M. pneumoniae infection in the fall/early winter.

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