Gut Microbiota and Immunity Relevance in Eubiosis and Dysbiosis

Overview

Journal Saudi J Biol Sci

Specialty Biology

Date 2022 Mar 14

PMID 35280528

Authors

Hanan E Al-Rashidi

Affiliations

Soon will be listed here.

Abstract

Human gut is colonized by numerous microorganisms, in which bacteria present the highest proportion of this colonization that live in a symbiotic relationship with the host. This microbial collection is commonly known as the microbiota. The gut microbiota can mediate gut epithelial and immune cells interaction through vitamins synthesis or metabolic products. The microbiota plays a vital role in growth and development of the main components of human's adaptive and innate immune system, while the immune system regulates host-microbe symbiosis. On the other hand, negative alteration in gut microbiota composition or gut dysbiosis, can disturb immune responses. This review highlights the gut microbiota-immune system cross-talk in both eubiosis and dysbiosis.

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