Age-dependent Perturbation of the Perceptual and Postural Vertical by Visual Roll Vection and Susceptibility to Motion Sickness in Children

Overview

Journal J Neurol

Specialty Neurology

Date 2022 Feb 25

PMID 35212790

Authors

Lutz Schnabel

Max Wuehr

Anna Huppert

Stanislav Bardins

Thomas Brandt

Doreen Huppert

Affiliations

Soon will be listed here.

Abstract

Background: The visual contribution to the perceptual and postural vertical is mediated by a multisensory integration process and may relate to children's susceptibility to motion sickness that is hypothesized to arise from intersensory conflicts.

Objective: To analyze the maturation of visual contribution to the perceptual and postural vertical in conjunction with the motion sickness susceptibility in childhood.

Methods: In 81 healthy children (aged 2-17 years; 57 females), adjustments of the subjective visual vertical and posturographically tested mediolateral displacements of body sway were measured during free upright stance and large-field visual motion stimulation in the roll plane (roll vection). Motion sickness susceptibility was assessed by taking the history of parents and children.

Results: Vection-induced tilts of the visual vertical showed a linear age-dependent decrease with largest tilts in the youngest (2-7 years; median of 20°) and smallest tilts in the oldest age group (13-17 years; median of 9-10°). Analogously, postural tilts as measured by mediolateral body sway were greatest in the youngest and smallest in the oldest age group. In contrast, motion sickness susceptibility was lowest in the youngest and highest in the oldest age group and exhibited an inverse correlation with vection-induced tilts of the visual vertical.

Conclusion: Roll vection-induced tilts of the visual and postural vertical exhibited a similar age-dependent course with the greatest effects in the youngest and the least effects in the oldest age group, the latter of which exhibited the highest susceptibility to motion sickness.

References

Dichgans J, Held R, Young L, Brandt T . Moving visual scenes influence the apparent direction of gravity. Science. 1972; 178(4066):1217-9. DOI: 10.1126/science.178.4066.1217. View

Butterworth G, Hicks L . Visual proprioception and postural stability in infancy. A developmental study. Perception. 1977; 6(3):255-62. DOI: 10.1068/p060255. View

Stoffregen T, Schmuckler M, Gibson E . Use of central and peripheral optical flow in stance and locomotion in young walkers. Perception. 1987; 16(1):113-9. DOI: 10.1068/p160113. View

Delorme A, Frigon J, Lagace C . Infants' reactions to visual movement of the environment. Perception. 1989; 18(5):667-73. DOI: 10.1068/p180667. View

Baumberger B, Isableu B, Fluckiger M . The visual control of stability in children and adults: postural readjustments in a ground optical flow. Exp Brain Res. 2004; 159(1):33-46. DOI: 10.1007/s00221-004-1930-1. View

Gaertner C, Bucci M, Obeid R, Wiener-Vacher S . Subjective visual vertical and postural performance in healthy children. PLoS One. 2013; 8(11):e79623. PMC: 3827351. DOI: 10.1371/journal.pone.0079623. View

Bucci M, Wiener-Vacher S, Trousson C, Baud O, Biran V . Subjective visual vertical and postural capability in children born prematurely. PLoS One. 2015; 10(3):e0121616. PMC: 4366151. DOI: 10.1371/journal.pone.0121616. View

Brandt T, Bauer M, Benson J, Huppert D . Motion sickness in ancient China: Seasickness and cart-sickness. Neurology. 2016; 87(3):331-5. DOI: 10.1212/WNL.0000000000002871. View

Zhang L, Wang J, Qi R, Pan L, Li M, Cai Y . Motion Sickness: Current Knowledge and Recent Advance. CNS Neurosci Ther. 2015; 22(1):15-24. PMC: 6492910. DOI: 10.1111/cns.12468. View

10.

Huppert D, Grill E, Brandt T . Survey of motion sickness susceptibility in children and adolescents aged 3 months to 18 years. J Neurol. 2019; 266(Suppl 1):65-73. DOI: 10.1007/s00415-019-09333-w. View

11.

Henriques I, Douglas de Oliveira D, Oliveira-Ferreira F, Andrade P . Motion sickness prevalence in school children. Eur J Pediatr. 2014; 173(11):1473-82. DOI: 10.1007/s00431-014-2351-1. View

12.

Dobie T, McBride D, Dobie Jr T, May J . The effects of age and sex on susceptibility to motion sickness. Aviat Space Environ Med. 2001; 72(1):13-20. View

13.

Scharoun S, Bryden P . Hand preference, performance abilities, and hand selection in children. Front Psychol. 2014; 5:82. PMC: 3927078. DOI: 10.3389/fpsyg.2014.00082. View

14.

Toupet M, Van Nechel C, Bozorg Grayeli A . Maturation of Subjective Visual Vertical in Children. Otol Neurotol. 2016; 37(6):761-6. DOI: 10.1097/MAO.0000000000001044. View

15.

Dieterich M, Brandt T . Ocular torsion and tilt of subjective visual vertical are sensitive brainstem signs. Ann Neurol. 1993; 33(3):292-9. DOI: 10.1002/ana.410330311. View

16.

Dieterich M, Brandt T . Perception of Verticality and Vestibular Disorders of Balance and Falls. Front Neurol. 2019; 10:172. PMC: 6457206. DOI: 10.3389/fneur.2019.00172. View

17.

Foster E, Sveistrup H, Woollacott M . Transitions in Visual Proprioception: A Cross-Sectional Developmental Study of the Effect of Visual Flow on Postural Control. J Mot Behav. 1996; 28(2):101-112. DOI: 10.1080/00222895.1996.9941737. View

18.

MONEY K . Motion sickness. Physiol Rev. 1970; 50(1):1-39. DOI: 10.1152/physrev.1970.50.1.1. View