Fetal Cardiac Parameters for Predicting Postnatal Operation Type of Fetuses with Tetralogy of Fallot

Overview

Journal Cardiovasc Ultrasound

Publisher Biomed Central

Specialties Cardiology & Vascular Diseases
Radiology

Date 2022 Feb 22

PMID 35189903

Authors

Suyeon Park

Hye-Sung Won

Rina Kim

Mijin Kim

Jeong Jin Yu

Chun Soo Park

Tae-Jin Yun

Yewon Jung

Usamah Al Harbi

Mi-Young Lee

Affiliations

Soon will be listed here.

Abstract

Background: To assess fetal cardiac parameters predictive of postnatal operation type in fetuses with tetralogy of Fallot (TOF).

Methods: Echocardiographic data obtained in the second and third trimesters were retrospectively reviewed for fetuses diagnosed with TOF between 2014 and 2018 at Asan Medical Center. The following fetal cardiac parameters were analyzed: 1) pulmonary valve annulus (PVA) z-score, 2) right pulmonary artery (RPA) z-score, 3) aortic valve annulus (AVA) z-score, 4) pulmonary valve peak systolic velocity (PV-PSV), 5) PVA/AVA ratio, and 6) RPA/descending aorta (DAo) ratio. These cardiac parameters were compared between a primary corrective surgery group and a palliative shunt operation followed by complete repair group.

Results: A total of 100 fetuses with TOF were included. Only one neonatal death occurred. Ninety patients underwent primary corrective surgery and 10 neonates underwent a multistage surgery. The PVA z-score, RPA z-score, and RPA/DAo ratio measured in the second trimester and the PVA z-score, RPA z-score, and PVA/AVA raio measured in the third trimester were significantly lower in the multistage surgery group, while the PV-PSV as measured in both trimesters were significantly higher in the multistage surgery group.

Conclusion: Fetal cardiac parameters are useful for predicting the operation type necessary for neonates with TOF.

Citing Articles

Three-dimensional/four-dimensional spatiotemporal image correlation morphology of the ductus arteriosus in fetuses with pulmonary atresia undergoing neonatal ductal stenting.

Karapurkar S, Gurav A, Sudhakar A, Sasikumar N, Kumar R, Vaidyanathan B Ann Pediatr Cardiol. 2024; 16(4):233-241.

PMID: 38343499 PMC: 10856608. DOI: 10.4103/apc.apc_95_23.

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