A Clinical Update on Vasoactive Medication in the Management of Cardiogenic Shock
Overview
Authors
Affiliations
This is a focused review looking at the pharmacological support in cardiogenic shock. There are a plethora of data evaluating vasopressors and inotropes in septic shock, but the data are limited for cardiogenic shock. This review article describes in detail the pathophysiology of cardiogenic shock, the mechanism of action of different vasopressors and inotropes emphasizing their indications and potential side effects. This review article incorporates the currently used specific risk-prediction models in cardiogenic shock as well as integrates data from many trials on the use of vasopressors and inotropes. Lastly, this review seeks to discuss the future direction for vasoactive medications in cardiogenic shock.
Ortega-Hernandez J, Gonzalez-Pacheco H, Araiza-Garaygordobil D, Gopar-Nieto R, Sierra-Lara-Martinez D, Manzur-Sandoval D Front Cardiovasc Med. 2025; 12:1461714.
PMID: 40017516 PMC: 11865078. DOI: 10.3389/fcvm.2025.1461714.
Mehta A, Bansal M, Belford P, Gilbert O, Zhao D, Vallabhajosyula S IHJ Cardiovasc Case Rep. 2024; 7(3-4):76-80.
PMID: 39450159 PMC: 11502143. DOI: 10.1016/j.ihjccr.2023.07.002.
Vallabhajosyula S, Sinha S, Kochar A, Pahuja M, Amico Jr F, Kapur N Curr Cardiol Rep. 2024; 26(10):1123-1134.
PMID: 39325244 DOI: 10.1007/s11886-024-02108-4.
Eraky A, Yerramalla Y, Khan A, Mokhtar Y, Alamrosy M, Farag A Int J Mol Sci. 2024; 25(15).
PMID: 39125627 PMC: 11311757. DOI: 10.3390/ijms25158058.
The Management of Cardiogenic Shock From Diagnosis to Devices: A Narrative Review.
Alkhunaizi F, Smith N, Brusca S, Furfaro D CHEST Crit Care. 2024; 2(2).
PMID: 38993934 PMC: 11238736. DOI: 10.1016/j.chstcc.2024.100071.