Challenge of Ziehl-Neelsen Stain for Basidiobolomycosis Diagnosis in Indonesia: A Unique Case Report

Overview

Journal Ann Med Surg (Lond)

Publisher Wolters Kluwer

Specialty Medical Education

Date 2022 Feb 11

PMID 35145665

Authors

Metta Octora

Arthur Pohan Kawilarang

Pepy Dwi Endraswari

Affiliations

Soon will be listed here.

Abstract

Background: Basidiobolomycosis is a rare fungal infection in Indonesia, so alternative investigations are needed to make a diagnosis.

Case Presentation: A 24-year-old male patient, Javanese, presented with Basidiobolomycosis. The patient had a lump on the right arm and face 2 years ago, and the tumor progressively grew up and extended to the right upper arm, neck, and face since 1 month ago. This paper discussed the challenge of Ziehl-Neelsen (ZN) stain as a diagnostic tool for Basidiobolomycosis that is a rare case in the world, especially in Indonesia.

Discussion: Acid-fast stain has never been used to diagnose fungal cases in general, but it could describe the hyphae and Splendore-Hoeppli very clearly compared to the standard hematoxylin and eosin (HE) stains.

Conclusion: ZN can be used as an alternative diagnosis of Basidiobolomycosis in a low-resource setting.

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