» Articles » PMID: 35125554

The Effect of Phytocompounds of Medicinal Plants on Coronavirus (2019-NCOV) Infection

Overview
Journal Pharm Chem J
Specialty Chemistry
Date 2022 Feb 7
PMID 35125554
Authors
Affiliations
Soon will be listed here.
Abstract

The recent outbreak of coronavirus disease 2019 (COVID-19) is a respiratory infection and it can spread from animal to person, person to person through coughing or physical contact. Recent studies revealed that the genome sequence of this pandemic disease is very similar to that of SARS-CoV, thus, there are not yet effective treatments that target the 2019-nCoV virus. Medicinal plants present a potential solution to resolve the drug problem. In fact, the bioactive compounds such as phenols, flavonoids, monoterpenes, and phenylpropanoids, derived from several herbs such as and could be used to develop formal drugs against several diseases with no or minimal side effects. In this paper, we describe the potential antiviral properties of several medicinal plants against Coronaviridae family viruses such as SARS, MERS, and IBV. Besides, we review various species of medicinal herbs and their derived phytochemical compounds in terms of their immunomodulatory bioactivities and antiviral activity.

Citing Articles

The Antiviral Potential of : Advances and Perspectives.

Chen J, Zhao Y, Cheng J, Wang H, Pan S, Liu Y Molecules. 2024; 29(14).

PMID: 39064906 PMC: 11279397. DOI: 10.3390/molecules29143328.


Insights into the stereoisomerism of dihydroquercetin: analytical and pharmacological aspects.

Terekhov R, Savina A, Pankov D, Korochkina M, Taldaev A, Yakubovich L Front Chem. 2024; 12:1439167.

PMID: 39050369 PMC: 11267486. DOI: 10.3389/fchem.2024.1439167.


Treating COVID-19 with Medicinal Plants: Is It Even Conceivable? A Comprehensive Review.

Al-Jamal H, Idriss S, Roufayel R, Khattar Z, Fajloun Z, Sabatier J Viruses. 2024; 16(3).

PMID: 38543686 PMC: 10974729. DOI: 10.3390/v16030320.


The mint versus Covid hypothesis.

Buck C Med Hypotheses. 2023; 173.

PMID: 37007799 PMC: 10062428. DOI: 10.1016/j.mehy.2023.111047.


Plants as Biofactories for Therapeutic Proteins and Antiviral Compounds to Combat COVID-19.

England C, TrejoMartinez J, PerezSanchez P, Karki U, Xu J Life (Basel). 2023; 13(3).

PMID: 36983772 PMC: 10054913. DOI: 10.3390/life13030617.


References
1.
Ben Sassi A, Harzallah-Skhiri F, Bourgougnon N, Aouni M . Antiviral activity of some Tunisian medicinal plants against Herpes simplex virus type 1. Nat Prod Res. 2007; 22(1):53-65. DOI: 10.1080/14786410701589790. View

2.
Jassim S, Naji M . Novel antiviral agents: a medicinal plant perspective. J Appl Microbiol. 2003; 95(3):412-27. DOI: 10.1046/j.1365-2672.2003.02026.x. View

3.
Ng K, Poon B, Puar T, Shan Quah J, Loh W, Wong Y . COVID-19 and the Risk to Health Care Workers: A Case Report. Ann Intern Med. 2020; 172(11):766-767. PMC: 7081171. DOI: 10.7326/L20-0175. View

4.
Ryu Y, Jae Jeong H, Kim J, Kim Y, Park J, Kim D . Biflavonoids from Torreya nucifera displaying SARS-CoV 3CL(pro) inhibition. Bioorg Med Chem. 2010; 18(22):7940-7. PMC: 7126309. DOI: 10.1016/j.bmc.2010.09.035. View

5.
Hammami S, Jmii H, El Mokni R, Khmiri A, Faidi K, Dhaouadi H . Essential Oil Composition, Antioxidant, Cytotoxic and Antiviral Activities of Teucrium pseudochamaepitys Growing Spontaneously in Tunisia. Molecules. 2015; 20(11):20426-33. PMC: 6331804. DOI: 10.3390/molecules201119707. View