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Development of the Gonadotropin-releasing Hormone System

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Specialty Endocrinology
Date 2022 Jan 24
PMID 35067985
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Abstract

This review summarizes the current understanding of the development of the neuroendocrine gonadotropin-releasing hormone (GnRH) system, including discussion on open questions regarding (1) transcriptional regulation of the Gnrh1 gene; (2) prenatal development of the GnRH1 system in rodents and humans; and (3) paracrine and synaptic communication during migration of the GnRH cells.

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