Biological Potential and Chemical Profile of European Varieties of

Overview

Journal Foods

Specialty Biotechnology

Date 2022 Jan 11

PMID 35010173

Authors

Natalia Pachura

Robert Kupczynski

Jordan Sycz

Agata Kuklinska

Anna Zwyrzykowska-Wodzinska

Katarzyna Winska

Aleksandra Owczarek

Piotr Kuropka

Renata Nowaczyk

Przemyslaw Babelewski

Antoni Szumny

Affiliations

Soon will be listed here.

Abstract

Plants of the genus are widespread throughout the world, with its best-known representative being from South America. The European species shows similarities in its terpenoid, sugar and phenolic acid profiles. Using aqueous extracts of as a supplement in Wistar rats showed that, despite the lack of caffeine, it had strong hypocholesterolemic effects. In addition, a reduction in oxidative lipid degradation and a decrease in hepatic steatosis in histopathological studies were observed. The results of this study suggest that extracts from the European species may have potential as an alternative treatment for hyperlipidemia.

Citing Articles

Antiviral and Cytotoxic Activities of Silver Queen in the Context of Chemical Profiling of Two Species.

Pachura N, Wlodarczyk M, Bazanow B, Pogorzelska A, Gebarowski T, Kupczynski R Molecules. 2024; 29(13).

PMID: 38999188 PMC: 11243556. DOI: 10.3390/molecules29133231.

Isolation of Biologically Active Compounds from L. Inflorescences by Using Different Extraction Solvents and Evaluation of Antimicrobial Activity.

Motiejauskaite D, Ullah S, Kundrotaite A, Zvirdauskiene R, Baksinskaite A, Barcauskaite K Antioxidants (Basel). 2023; 12(5).

PMID: 37237864 PMC: 10215227. DOI: 10.3390/antiox12050998.

Assessing Phenotypic Variability in Some Eastern European Insular Populations of the Climatic Relict L.

Mihali C, Petrescu C, Ciolacu-Ladasiu C, Mathe E, Popescu C, Bota V Plants (Basel). 2022; 11(15).

PMID: 35956499 PMC: 9370372. DOI: 10.3390/plants11152022.

Biochemical and Molecular Investigation of the Effect of Saponins and Terpenoids Derived from Leaves of on Lipid Metabolism of Obese Zucker Rats.

Pachura N, Kupczynski R, Lewandowska K, Wlodarczyk M, Klemens M, Kuropka P Molecules. 2022; 27(11).

PMID: 35684317 PMC: 9182309. DOI: 10.3390/molecules27113376.

References

Thoppil R, Bishayee A . Terpenoids as potential chemopreventive and therapeutic agents in liver cancer. World J Hepatol. 2011; 3(9):228-49. PMC: 3182282. DOI: 10.4254/wjh.v3.i9.228. View

Arcari D, Bartchewsky W, dos Santos T, Oliveira K, Funck A, Pedrazzoli J . Antiobesity effects of yerba maté extract (Ilex paraguariensis) in high-fat diet-induced obese mice. Obesity (Silver Spring). 2009; 17(12):2127-33. DOI: 10.1038/oby.2009.158. View

Bracesco N, Sanchez A, CONTRERAS V, Menini T, Gugliucci A . Recent advances on Ilex paraguariensis research: minireview. J Ethnopharmacol. 2010; 136(3):378-84. DOI: 10.1016/j.jep.2010.06.032. View

Evens Z, Stellpflug S . Holiday plants with toxic misconceptions. West J Emerg Med. 2013; 13(6):538-42. PMC: 3555592. DOI: 10.5811/westjem.2012.8.12572. View

Pereira A, Tirapeli K, Chaves-Neto A, Brasilino M, Rocha C, Bello-Klein A . Ilex paraguariensis supplementation may be an effective nutritional approach to modulate oxidative stress during perimenopause. Exp Gerontol. 2017; 90:14-18. DOI: 10.1016/j.exger.2017.01.011. View

Lutomski P, Gozdziewska M, Florek-Luszczki M . Health properties of Yerba Mate. Ann Agric Environ Med. 2020; 27(2):310-313. DOI: 10.26444/aaem/119994. View

Valduga A, Goncalves I, Magri E, Delalibera Finzer J . Chemistry, pharmacology and new trends in traditional functional and medicinal beverages. Food Res Int. 2019; 120:478-503. DOI: 10.1016/j.foodres.2018.10.091. View

Siddiqui N, Al-Yousef H, Alhowiriny T, Alam P, Hassan W, Amina M . Concurrent analysis of bioactive triterpenes oleanolic acid and β-amyrin in antioxidant active fractions of , and grown in Saudi Arabia by applying validated HPTLC method. Saudi Pharm J. 2018; 26(2):266-273. PMC: 6111195. DOI: 10.1016/j.jsps.2017.11.013. View

Negrin A, Long C, Motley T, Kennelly E . LC-MS Metabolomics and Chemotaxonomy of Caffeine-Containing Holly ( Ilex) Species and Related Taxa in the Aquifoliaceae. J Agric Food Chem. 2019; 67(19):5687-5699. DOI: 10.1021/acs.jafc.8b07168. View

10.

Wei A, Shibamoto T . Antioxidant activities and volatile constituents of various essential oils. J Agric Food Chem. 2007; 55(5):1737-42. DOI: 10.1021/jf062959x. View

11.

Arcari D, Bartchewsky Jr W, dos Santos T, Oliveira K, DeOliveira C, Gotardo E . Anti-inflammatory effects of yerba maté extract (Ilex paraguariensis) ameliorate insulin resistance in mice with high fat diet-induced obesity. Mol Cell Endocrinol. 2011; 335(2):110-5. DOI: 10.1016/j.mce.2011.01.003. View

12.

Im K, Jeong T, Kwon B, Baek N, Kim S, Kim D . Acyl-CoA: cholesterol acyltransferase inhibitors from Ilex macropoda. Arch Pharm Res. 2006; 29(3):191-4. DOI: 10.1007/BF02969391. View

13.

Topcu G . Bioactive triterpenoids from Salvia species. J Nat Prod. 2006; 69(3):482-7. DOI: 10.1021/np0600402. View

14.

Serviddio G, Bellanti F, Villani R, Tamborra R, Zerbinati C, Blonda M . Effects of dietary fatty acids and cholesterol excess on liver injury: A lipidomic approach. Redox Biol. 2016; 9:296-305. PMC: 5026694. DOI: 10.1016/j.redox.2016.09.002. View

15.

Gao H, Liu Z, Wan W, Qu X, Chen M . Aqueous extract of Yerba Mate tea lowers atherosclerotic risk factors in a rat hyperlipidemia model. Phytother Res. 2012; 27(8):1225-31. DOI: 10.1002/ptr.4856. View

16.

Becker M, Liebner F, Rosenau T, Potthast A . Ethoximation-silylation approach for mono- and disaccharide analysis and characterization of their identification parameters by GC/MS. Talanta. 2013; 115:642-51. DOI: 10.1016/j.talanta.2013.05.052. View

17.

Santos F, Frota J, Rodrigues Arruda B, Melo T, de Carvalho Almeida da Silva A, Brito G . Antihyperglycemic and hypolipidemic effects of α, β-amyrin, a triterpenoid mixture from Protium heptaphyllum in mice. Lipids Health Dis. 2012; 11:98. PMC: 3484111. DOI: 10.1186/1476-511X-11-98. View

18.

Goto T, Takahashi N, Hirai S, Kawada T . Various Terpenoids Derived from Herbal and Dietary Plants Function as PPAR Modulators and Regulate Carbohydrate and Lipid Metabolism. PPAR Res. 2010; 2010:483958. PMC: 2896613. DOI: 10.1155/2010/483958. View

19.

Heck C, De Mejia E . Yerba Mate Tea (Ilex paraguariensis): a comprehensive review on chemistry, health implications, and technological considerations. J Food Sci. 2007; 72(9):R138-51. DOI: 10.1111/j.1750-3841.2007.00535.x. View

20.

da Silva B, Dias D, de Castro Moreira M, Toledo R, da Matta S, Della Lucia C . Chia Seed Shows Good Protein Quality, Hypoglycemic Effect and Improves the Lipid Profile and Liver and Intestinal Morphology of Wistar Rats. Plant Foods Hum Nutr. 2016; 71(3):225-30. DOI: 10.1007/s11130-016-0543-8. View