Relationship Between Braden Scale Scores and Acute Kidney Injury Among Patients with Acute Coronary Syndrome: a Multicentre Retrospective Cohort Study

Overview

Journal BMJ Open

Specialty General Medicine

Date 2022 Jan 6

PMID 34987039

Authors

Zhichao Li

Bofu Liu

Dongze Li

Yu Jia

Lei Ye

Xiaoyang Liao

Zhi Zeng

Zhi Wan

Affiliations

Soon will be listed here.

Abstract

Objectives: To evaluate the impact of pressure ulcer events assessed by the Braden Scale (BS) on acute kidney injury (AKI) in patients with acute coronary syndrome (ACS).

Design: A multicentre retrospective cohort study.

Setting: Chest pain centres from seven tertiary hospitals in China.

Participants: We analysed 3185 patients with ACS from the Retrospective Evaluation of Acute Chest Pain study. The patients were divided into three groups (B1, B2 and B3) according to their BS scores (≤12 vs 13-14 vs ≥15, respectively) at admission.

Outcome Measures: AKI was defined according to the criteria of the 2012 Kidney Disease: Improving Global Outcomes. Multivariate logistic analysis was used to evaluate the relationship between the BS score and AKI.

Results: There were 461 patients (14.5%) with ACS who had the complication of AKI. Patients with a lower score on the BS had a higher incidence of AKI (p<0.001). Multivariate logistic regression analysis showed that adjusted ORs of the BS score for AKI were 2.242 (B1 vs B3: 95% CI: 1.643 to 3.060, p<0.001) and 1.566 (B2 vs B3: 95% CI: 1.186 to 2.069, p=0.002). The receiver operating characteristic curve analysis showed that the area under the curve of the BS score was 0.719 (95% CI: 0.702 to 0.736; p<0.001) for AKI.

Conclusions: The BS score was independently associated with AKI. It may be a useful tool to identify those who may benefit from further prediction and prevention of AKI in patients with ACS.

Trail Registration Number: ChiCTR1900024657 (http://www.chictr.org.cn/). The satge rekates to results.

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