Assembly of RNA Nanostructures from Double-Crossover Tiles

Overview

Journal Methods Mol Biol

Specialty Molecular Biology

Date 2022 Jan 5

PMID 34985752

Authors

Jaimie Marie Stewart

Hari K K Subramanian

Elisa Franco

Affiliations

Soon will be listed here.

Abstract

Artificial self-assembling RNA scaffolds can be produced from many types of RNA motifs that are rationally designed. These scaffolds are of interest as nanoscale organizers, with applications in drug delivery and synthetic cells. Here we describe design strategies, production methods, and imaging of micrometer-sized RNA nanotubes and lattices that assemble from RNA tiles comprising multiple distinct strands.

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