Strategies for Articular Cartilage Repair and Regeneration

Overview

Journal Front Bioeng Biotechnol

Date 2022 Jan 3

PMID 34976967

Citations 47

Authors

Yanxi Liu

Karan M Shah

Jian Luo

Affiliations

Soon will be listed here.

Abstract

Articular cartilage is an avascular tissue, with limited ability to repair and self-renew. Defects in articular cartilage can induce debilitating degenerative joint diseases such as osteoarthritis. Currently, clinical treatments have limited ability to repair, for they often result in the formation of mechanically inferior cartilage. In this review, we discuss the factors that affect cartilage homeostasis and function, and describe the emerging regenerative approaches that are informing the future treatment options.

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