Ofloxacin Vs. Cotrimoxazole in Patients with Complicated Urinary Tract Infections

Overview

Journal Int J Clin Pharmacol Ther Toxicol

Specialty Pharmacology

Date 1987 May 1

PMID 3496284

Citations 4

Authors

A VELLUCCI

G Bernardini

A M Battaglia

P Battaglia

Affiliations

Soon will be listed here.

Abstract

A simple open randomized study was performed to evaluate the comparative efficacy and safety of ofloxacin and cotrimoxazole in 40 patients with complicated urinary tract infections. In these patients ofloxacin produced better clinical results than cotrimoxazole. The results were also excellent when cotrimoxazole-resistant strains were involved, even in immunocompromised hosts.

Citing Articles

Randomized, double-blind comparison of ciprofloxacin and trimethoprim-sulfamethoxazole for complicated urinary tract infections.

Allais J, Preheim L, Cuevas T, Roccaforte J, Mellencamp M, Bittner M Antimicrob Agents Chemother. 1988; 32(9):1327-30.

PMID: 3195995 PMC: 175861. DOI: 10.1128/AAC.32.9.1327.

Ofloxacin versus trimethoprim-sulfamethoxazole for treatment of acute cystitis.

Hooton T, Latham R, Wong E, JOHNSON C, Roberts P, Stamm W Antimicrob Agents Chemother. 1989; 33(8):1308-12.

PMID: 2802557 PMC: 172645. DOI: 10.1128/AAC.33.8.1308.

Single-dose and three-day regimens of ofloxacin versus trimethoprim-sulfamethoxazole for acute cystitis in women.

Hooton T, JOHNSON C, Winter C, Kuwamura L, Rogers M, Roberts P Antimicrob Agents Chemother. 1991; 35(7):1479-83.

PMID: 1929311 PMC: 245194. DOI: 10.1128/AAC.35.7.1479.

Ofloxacin. A reappraisal of its antimicrobial activity, pharmacology and therapeutic use.

Todd P, Faulds D Drugs. 1991; 42(5):825-76.

PMID: 1723377 DOI: 10.2165/00003495-199142050-00008.