Selective Para-C-H Alkynylation of Aniline Derivatives by Pd/S,O-Ligand Catalysis

Overview

Journal Chemistry

Specialty Chemistry

Date 2021 Dec 13

PMID 34902180

Citations 2

Authors

Ke-Zuan Deng

Wen-Liang Jia

M Angeles Fernandez-Ibanez

Affiliations

Soon will be listed here.

Abstract

Herein, we report a nondirected para-selective C-H alkynylation of aniline derivatives by a Pd/S,O-ligand-based catalyst. The reaction proceeds under mild conditions and is compatible with a variety of substituted anilines. The scalability and further derivatizations of the alkynylated products have been also demonstrated.

Citing Articles

Palladium-Catalyzed C-H Arylation of Unprotected Anilines: Chemo- and Regioselectivity Enabled by the Cooperating Ligand [2,2'-Bipyridin]-6(1)-one.

Pinilla C, Salamanca V, Lledos A, Albeniz A ACS Catal. 2022; 12(23):14527-14532.

PMID: 36504914 PMC: 9724229. DOI: 10.1021/acscatal.2c05206.

Selective Para-C-H Alkynylation of Aniline Derivatives by Pd/S,O-Ligand Catalysis.

Deng K, Jia W, Fernandez-Ibanez M Chemistry. 2021; 28(9):e202104107.

PMID: 34902180 PMC: 9306564. DOI: 10.1002/chem.202104107.

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