» Articles » PMID: 34901098

Rapid Progression of Angioimmunoblastic T Cell Lymphoma Following BNT162b2 MRNA Vaccine Booster Shot: A Case Report

Overview
Specialty General Medicine
Date 2021 Dec 13
PMID 34901098
Citations 29
Authors
Affiliations
Soon will be listed here.
Abstract

Since nucleoside-modified mRNA vaccines strongly activate T follicular helper cells, it is important to explore the possible impact of approved SARS-CoV-2 mRNA vaccines on neoplasms affecting this cell type. Herein, we report and discuss unexpected rapid progression of lymphomatous lesions after administration of a BNT162b2 mRNA vaccine booster in a man recently diagnosed with AITL.

Citing Articles

The WHO Algorithm for Causality Assessment of Adverse Effects Following Immunization with Genetic-Based Anti-COVID-19 Vaccines: Pitfalls and Suggestions for Improvement.

Bellavite P, Donzelli A, Isidoro C J Clin Med. 2024; 13(23).

PMID: 39685749 PMC: 11642405. DOI: 10.3390/jcm13237291.


Nodal T-Follicular Helper Cell Lymphoma, Angioimmunoblastic-Type, Diagnosed in a Patient with Psoriasis Following COVID-19 Vaccination under Adalimumab Treatment: A Causal Association?.

Hsieh C, Yu S, Lee J, Tsai T Indian J Dermatol. 2024; 69(3):264-267.

PMID: 39119326 PMC: 11305510. DOI: 10.4103/ijd.ijd_93_23.


Diagnosis of Angioimmunoblastic T Cell Lymphoma After Receiving First Dose of Pfizer/BioNTech (BNT162b2) Vaccine: A Case Report.

Khatri J, Tahboub I, Anwar K, Masoudi M, Graffeo V, Jamil M J Investig Med High Impact Case Rep. 2024; 12:23247096241231645.

PMID: 38761096 PMC: 11102676. DOI: 10.1177/23247096241231645.


Increased Age-Adjusted Cancer Mortality After the Third mRNA-Lipid Nanoparticle Vaccine Dose During the COVID-19 Pandemic in Japan.

Gibo M, Kojima S, Fujisawa A, Kikuchi T, Fukushima M Cureus. 2024; 16(4):e57860.

PMID: 38721172 PMC: 11077472. DOI: 10.7759/cureus.57860.


Rare COVID-19 vaccine side effects got lost in the shuffle. Primary cutaneous lymphomas following COVID-19 vaccination: a systematic review.

Olszewska B, Zaryczanska A, Nowicki R, Sokolowska-Wojdylo M Front Med (Lausanne). 2024; 11:1325478.

PMID: 38660418 PMC: 11041019. DOI: 10.3389/fmed.2024.1325478.


References
1.
Kitadate A, Narita K, Fukumoto K, Terao T, Tsushima T, Kobayashi H . Baseline total lesion glycolysis combined with interim positron emission tomography-computed tomography is a robust predictor of outcome in patients with peripheral T-cell lymphoma. Cancer Med. 2020; 9(15):5509-5518. PMC: 7402824. DOI: 10.1002/cam4.3226. View

2.
Loetsch C, Warren J, Laskowski A, Vazquez-Lombardi R, Jandl C, Langley D . Cytosolic Recognition of RNA Drives the Immune Response to Heterologous Erythrocytes. Cell Rep. 2017; 21(6):1624-1638. DOI: 10.1016/j.celrep.2017.10.044. View

3.
Turner J, OHalloran J, Kalaidina E, Kim W, Schmitz A, Zhou J . SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses. Nature. 2021; 596(7870):109-113. PMC: 8935394. DOI: 10.1038/s41586-021-03738-2. View

4.
Keshavarz P, Yazdanpanah F, Rafiee F, Mizandari M . Lymphadenopathy Following COVID-19 Vaccination: Imaging Findings Review. Acad Radiol. 2021; 28(8):1058-1071. PMC: 8088218. DOI: 10.1016/j.acra.2021.04.007. View

5.
Horwitz S, OConnor O, Pro B, Illidge T, Fanale M, Advani R . Brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial. Lancet. 2018; 393(10168):229-240. PMC: 6436818. DOI: 10.1016/S0140-6736(18)32984-2. View