» Articles » PMID: 34888197

A Review of Deep Learning-based Three-dimensional Medical Image Registration Methods

Overview
Specialty Radiology
Date 2021 Dec 10
PMID 34888197
Citations 18
Authors
Affiliations
Soon will be listed here.
Abstract

Medical image registration is a vital component of many medical procedures, such as image-guided radiotherapy (IGRT), as it allows for more accurate dose-delivery and better management of side effects. Recently, the successful implementation of deep learning (DL) in various fields has prompted many research groups to apply DL to three-dimensional (3D) medical image registration. Several of these efforts have led to promising results. This review summarized the progress made in DL-based 3D image registration over the past 5 years and identify existing challenges and potential avenues for further research. The collected studies were statistically analyzed based on the region of interest (ROI), image modality, supervision method, and registration evaluation metrics. The studies were classified into three categories: deep iterative registration, supervised registration, and unsupervised registration. The studies are thoroughly reviewed and their unique contributions are highlighted. A summary is presented following a review of each category of study, discussing its advantages, challenges, and trends. Finally, the common challenges for all categories are discussed, and potential future research topics are identified.

Citing Articles

Artificial Intelligence-Empowered Radiology-Current Status and Critical Review.

Obuchowicz R, Lasek J, Wodzinski M, Piorkowski A, Strzelecki M, Nurzynska K Diagnostics (Basel). 2025; 15(3).

PMID: 39941212 PMC: 11816879. DOI: 10.3390/diagnostics15030282.


Enhancing unsupervised learning in medical image registration through scale-aware context aggregation.

Liu Y, Wang L, Ning X, Gao Y, Wang D iScience. 2025; 28(2):111734.

PMID: 39898031 PMC: 11787544. DOI: 10.1016/j.isci.2024.111734.


Development and validation of a multi-parametric MRI deep-learning model for preoperative lymphovascular invasion evaluation in rectal cancer.

Shi S, Singh A, Ma J, Nie X, Kong X, Xiao L Quant Imaging Med Surg. 2025; 15(1):427-439.

PMID: 39839029 PMC: 11744136. DOI: 10.21037/qims-24-789.


A survey on deep learning in medical image registration: New technologies, uncertainty, evaluation metrics, and beyond.

Chen J, Liu Y, Wei S, Bian Z, Subramanian S, Carass A Med Image Anal. 2024; 100():103385.

PMID: 39612808 PMC: 11730935. DOI: 10.1016/j.media.2024.103385.


Navigating the innovation policy dilemma: How subnational governments balance expenditure competition pressures and long-term innovation goals.

Song W, Zhao K Heliyon. 2024; 10(15):e34787.

PMID: 39145017 PMC: 11320305. DOI: 10.1016/j.heliyon.2024.e34787.


References
1.
Onieva J, Marti-Fuster B, de la Puente M, San Jose Estepar R . Diffeomorphic Lung Registration Using Deep CNNs and Reinforced Learning. Image Anal Mov Organ Breast Thorac Images (2018). 2020; 11040:284-294. PMC: 7266290. DOI: 10.1007/978-3-030-00946-5_28. View

2.
Vishnevskiy V, Gass T, Szekely G, Tanner C, Goksel O . Isotropic Total Variation Regularization of Displacements in Parametric Image Registration. IEEE Trans Med Imaging. 2016; 36(2):385-395. DOI: 10.1109/TMI.2016.2610583. View

3.
Verellen D, De Ridder M, Linthout N, Tournel K, Soete G, Storme G . Innovations in image-guided radiotherapy. Nat Rev Cancer. 2007; 7(12):949-60. DOI: 10.1038/nrc2288. View

4.
Zhu Z, Cao Y, Qin C, Rao Y, Lin D, Dou Q . Joint affine and deformable three-dimensional networks for brain MRI registration. Med Phys. 2020; 48(3):1182-1196. DOI: 10.1002/mp.14674. View

5.
Marcus D, Wang T, Parker J, Csernansky J, Morris J, Buckner R . Open Access Series of Imaging Studies (OASIS): cross-sectional MRI data in young, middle aged, nondemented, and demented older adults. J Cogn Neurosci. 2007; 19(9):1498-507. DOI: 10.1162/jocn.2007.19.9.1498. View