Bioactive Phytochemicals with Anti-Aging and Lifespan Extending Potentials in

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2021 Dec 10

PMID 34885907

Citations 16

Authors

Nkwachukwu Oziamara Okoro

Arome Solomon Odiba

Patience Ogoamaka Osadebe

Edwin Ogechukwu Omeje

Guiyan Liao

Wenxia Fang

Cheng Jin

Bin Wang

Affiliations

Soon will be listed here.

Abstract

In the forms of either herbs or functional foods, plants and their products have attracted medicinal, culinary, and nutraceutical applications due to their abundance in bioactive phytochemicals. Human beings and other animals have employed those bioactive phytochemicals to improve health quality based on their broad potentials as antioxidant, anti-microbial, anti-carcinogenic, anti-inflammatory, neuroprotective, and anti-aging effects, amongst others. For the past decade and half, efforts to discover bioactive phytochemicals both in pure and crude forms have been intensified using the aging model, in which various metabolic pathways in humans are highly conserved. In this review, we summarized the aging and longevity pathways that are common to and humans and collated some of the bioactive phytochemicals with health benefits and lifespan extending effects that have been studied in . This simple animal model is not only a perfect system for discovering bioactive compounds but is also a research shortcut for elucidating the amelioration mechanisms of aging risk factors and associated diseases.

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