From Salt to Hypertension, What is Missed?

Overview

Journal J Clin Hypertens (Greenwich)

Specialty Cardiology & Vascular Diseases

Date 2021 Nov 30

PMID 34846798

Citations 3

Authors

Zhiyi Ma

Scott L Hummel

Ningling Sun

Yuanyuan Chen

Affiliations

Soon will be listed here.

Abstract

Excess salt intake is viewed as a major contributor to hypertension and cardiovascular disease, and dietary salt restriction is broadly recommended by public health guidelines. However, individuals can have widely varying physiological responses to salt intake, and a tailored approach to evaluation and intervention may be needed. The traditional sodium related concepts are challenging to assess clinically for two reasons: (1) spot and 24-hour urine sodium are frequently used to evaluate salt intake, but are more suitable for population study, and (2) some adverse effects of salt may be blood pressure-independent. In recent years, previously unknown mechanisms of sodium absorption and storage have been discovered. This review will outline the limitations of current methods to assess sodium balance and discuss new potential evaluation methods and treatment targets.

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From salt to hypertension, what is missed?.

Ma Z, Hummel S, Sun N, Chen Y J Clin Hypertens (Greenwich). 2021; 23(12):2033-2041.

PMID: 34846798 PMC: 8696232. DOI: 10.1111/jch.14402.

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