-related Lung Disease in People with Cystic Fibrosis: Can Imaging Help Us to Diagnose Disease?

Overview

Journal Eur Respir Rev

Specialty Pulmonary Medicine

Date 2021 Nov 18

PMID 34789463

Citations 5

Authors

Qianting Lv

Bernadette B L J Elders

Adilia Warris

Daan Caudri

Pierluigi Ciet

Harm A W M Tiddens

Affiliations

Soon will be listed here.

Abstract

In people with cystic fibrosis (PwCF), viscous sputum and dysfunction of the mucociliary escalator leads to early and chronic infections. The prevalence of in sputum is high in PwCF and the contribution of to the progression of structural lung disease has been reported. However, overall, relatively little is known about the contribution of to CF lung disease. More knowledge is needed to aid clinical decisions on whether to start antifungal treatment. In this review, we give an overview of colonisation and infection in PwCF and the different types of pulmonary disease caused by it Furthermore, we discuss the current evidence for structural lung damage associated with in PwCF on chest computed tomography and magnetic resonance imaging. We conclude that radiological outcomes to identify disease caused by can be important for clinical studies and management.

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