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A Combination of Bohr and Haldane Effects Provide a Physiologic Explanation for the Increase in Arterial Oxygen Saturation when a Face Mask is Added to a High-flow Nasal Cannula in Severely Hypoxemic COVID-19 Patients

Overview
Journal Crit Care
Specialty Critical Care
Date 2021 Nov 17
PMID 34784946
Citations 2
Authors
Pablo Born
Ricardo Castro
Affiliations
Soon will be listed here.
Citing Articles

Combining reservoir mask oxygenation with high-flow nasal cannula in the treatment of hypoxemic respiratory failure among patients with COVID-19 pneumonia: a retrospective cohort study.

Gur I, Zalts R, Dotan Y, Hussain K, Neuberger A, Fuchs E Acute Crit Care. 2023; 38(4):435-441.

PMID: 37994019 PMC: 10718500. DOI: 10.4266/acc.2023.00451.

A combination of Bohr and Haldane effects provide a physiologic explanation for the increase in arterial oxygen saturation when a face mask is added to a high-flow nasal cannula in severely hypoxemic COVID-19 patients.

Born P, Castro R Crit Care. 2021; 25(1):395.

PMID: 34784946 PMC: 8593628. DOI: 10.1186/s13054-021-03791-3.

References
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Montiel V, Robert A, Robert A, Nabaoui A, Marie T, Morales Mestre N . Surgical mask on top of high-flow nasal cannula improves oxygenation in critically ill COVID-19 patients with hypoxemic respiratory failure. Ann Intensive Care. 2020; 10(1):125. PMC: 7523252. DOI: 10.1186/s13613-020-00744-x. View
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MacDonald R . Red cell 2,3-diphosphoglycerate and oxygen affinity. Anaesthesia. 1977; 32(6):544-53. DOI: 10.1111/j.1365-2044.1977.tb10002.x. View
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Born P, Castro R . A combination of Bohr and Haldane effects provide a physiologic explanation for the increase in arterial oxygen saturation when a face mask is added to a high-flow nasal cannula in severely hypoxemic COVID-19 patients. Crit Care. 2021; 25(1):395. PMC: 8593628. DOI: 10.1186/s13054-021-03791-3. View
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Christiansen J, Douglas C, Haldane J . The absorption and dissociation of carbon dioxide by human blood. J Physiol. 1914; 48(4):244-71. PMC: 1420520. DOI: 10.1113/jphysiol.1914.sp001659. View
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Swenson E . Does inspiration of exhaled CO explain improved oxygenation with a face mask plus high-flow nasal cannula oxygen in severe COVID-19 infection?. Crit Care. 2021; 25(1):343. PMC: 8451384. DOI: 10.1186/s13054-021-03771-7. View