Polycythaemia Rubra Vera Transforming to Acute Lymphoblastic Leukaemia

Overview

Journal Clin Lab Haematol

Specialty Hematology

Date 1987 Jan 1

PMID 3476236

Citations 5

Authors

R Aitchison

A J Black

M F Greaves

Affiliations

Soon will be listed here.

Abstract

Two patients who developed acute lymphoblastic leukaemia following polycythaemia rubra vera (PRV) are described. In both cases the diagnosis was made using cytochemistry and immunological markers. One patient's cells marked as T-cell acute lymphoblastic leukaemia (T-ALL), the other as unclassified (null) ALL. These cases support the concept that PRV is a stem cell disorder.

Citing Articles

The development of T-cell malignancies in patients with pre-existing myeloproliferative neoplasms: a report of three cases.

Burns E, Anand K, Chung B, Shah S, Randhawa J, Pingali S Ecancermedicalscience. 2020; 14:1011.

PMID: 32256694 PMC: 7105335. DOI: 10.3332/ecancer.2020.1011.

Acute lymphoblastic leukemia secondary to myeloproliferative neoplasms or after lenalidomide exposure.

Alhuraiji A, Naqvi K, Huh Y, Ho C, Verstovsek S, Bose P Clin Case Rep. 2018; 6(1):155-161.

PMID: 29375856 PMC: 5771935. DOI: 10.1002/ccr3.1264.

Acute Lymphoblastic Leukemia Transformation in Polycythemia Vera: A Rare Phenomenon.

Gawel W, Helbig G, Boral K, Kyrcz-Krzemien S Indian J Hematol Blood Transfus. 2016; 32(Suppl 1):62-5.

PMID: 27408357 PMC: 4925563. DOI: 10.1007/s12288-016-0673-z.

Acute Lymphoblastic Leukemia Arising in CALR Mutated Essential Thrombocythemia.

Langabeer S, Haslam K, OBrien D, Kelly J, Andrews C, Ryan C Case Rep Hematol. 2016; 2016:6545861.

PMID: 26904322 PMC: 4745278. DOI: 10.1155/2016/6545861.

Polycythaemia rubra vera transforming to acute lymphoblastic leukaemia with a common immunophenotype.

Neilson J, Patton W, Williams M, Mayne E, Boughton B J Clin Pathol. 1994; 47(5):471-2.

PMID: 8027406 PMC: 502032. DOI: 10.1136/jcp.47.5.471.