On-Site, On-Demand 3D-Printed Nasopharyngeal Swabs to Improve the Access of Coronavirus Disease-19 Testing

Overview

Journal Glob Chall

Date 2021 Nov 10

PMID 34754507

Citations 2

Authors

Jiaxi Song

Jeremy Korunes-Miller

Rohin Banerji

Yuanqiao Wu

Shoreh Fazeli

Hanqiao Zheng

Beverley Orr

Elise Morgan

Christopher Andry

Joel Henderson

Nancy S Miller

Alice White

Mark W Grinstaff

Affiliations

Soon will be listed here.

Abstract

Diagnostic testing that facilitates containment, surveillance, and treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), or future respiratory viruses, depends on a sample collection device that efficiently collects nasopharyngeal tissue and that can be manufactured on site when an outbreak or public health emergency is declared by a government. Here two novel stereolithography-based three-dimensional (3D)-printed nasopharyngeal swabs are reported which are made using a biocompatible and sterilizable photoresist. Such swabs are readily manufactured on-site and on-demand to ensure availability, if supply chain shortages emerge. Additionally, the 3D-printed swabs easily adapt to current workflow and testing procedures in hospital clinical laboratories to allow for effortless scaling up of test kits. Finally, the 3D-printed nasopharyngeal swabs demonstrate concordant SARS-CoV-2 testing results between the 3D-printed swabs and the COPAN commercial swabs, and enable detection of SARS-CoV-2 in clinical samples obtained from autopsies.

Citing Articles

Original article: novelty of Canadian manufacture nasopharyngeal swabs for collection of samples being tested for SARS-CoV-2 in a pandemic setting.

Palomino-Padilla S, Caceres-Cardenas G, Calderon R, Ko A, Garnett L, Doan K Front Public Health. 2024; 12:1344295.

PMID: 38784579 PMC: 11111943. DOI: 10.3389/fpubh.2024.1344295.

On-Site, On-Demand 3D-Printed Nasopharyngeal Swabs to Improve the Access of Coronavirus Disease-19 Testing.

Song J, Korunes-Miller J, Banerji R, Wu Y, Fazeli S, Zheng H Glob Chall. 2021; 5(11):2100039.

PMID: 34754507 PMC: 8562062. DOI: 10.1002/gch2.202100039.

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