Practical Fundamentals of Clinical MEG Interpretation in Epilepsy

Overview

Journal Front Neurol

Specialty Neurology

Date 2021 Nov 1

PMID 34721261

Citations 12

Authors

Christopher Laohathai

John S Ebersole

John C Mosher

Anto I Bagic

Ai Sumida

Gretchen Von Allmen

Michael E Funke

Affiliations

Soon will be listed here.

Abstract

Magnetoencephalography (MEG) is a neurophysiologic test that offers a functional localization of epileptic sources in patients considered for epilepsy surgery. The understanding of clinical MEG concepts, and the interpretation of these clinical studies, are very involving processes that demand both clinical and procedural expertise. One of the major obstacles in acquiring necessary proficiency is the scarcity of fundamental clinical literature. To fill this knowledge gap, this review aims to explain the basic practical concepts of clinical MEG relevant to epilepsy with an emphasis on single equivalent dipole (sECD), which is one the most clinically validated and ubiquitously used source localization method, and illustrate and explain the regional topology and source dynamics relevant for clinical interpretation of MEG-EEG.

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