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The Association Between the Binding Processes of Working Memory and Vascular Risk Profile in Adults

Overview
Journal Brain Sci
Publisher MDPI
Date 2021 Sep 28
PMID 34573162
Citations 3
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Abstract

Episodic buffer (EB), a key component of working memory, seems to have a rather complicated function as part of binding processes. Recent papers on the field claim that binding processes of working memory (WM) are assisted by attention and executive functions. On the same page, vascular pathology is gaining more ground as the main underlying cause for many brain pathologies. Hypercholesterolemia, hypertension, obesity, diabetes, lack of exercise and smoking are the most common risk factors that people of all ages suffer from and constitute the main vascular risk factors responsible for a possible decline in executive functions and attention. Thus, this research is an attempt to examine the relation between the binding functions of WM and the existence of vascular risk factors via a computerized test focusing on feature binding. The study comprised adults (n = 229) with and without vascular risk factors. The main tools used were a biomarker questionnaire and a feature binding test (FBT). The results showed that participants who report suffering from one or more vascular risk factors had significantly lower performance on specific subtasks of the FBT in comparison to the participants who were healthy. This allows us to assume that there might be a positive association between feature binding and a vascular risk profile in adults, and such a test could be a useful diagnostic tool for early cognitive impairment due to incipient vascular pathology.

Citing Articles

The Mixed Role of Sleep and Time of Day in Working Memory Performance of Older Adults with Mild Cognitive Impairment.

Georgoudas M, Moraitou D, Poptsi E, Tsardoulias E, Kesanli D, Papaliagkas V Healthcare (Basel). 2024; 12(16).

PMID: 39201180 PMC: 11353340. DOI: 10.3390/healthcare12161622.


Trajectories of Cognitive Impairment in Adults Bearing Vascular Risk Factors, with or without Diagnosis of Mild Cognitive Impairment: Findings from a Longitudinal Study Assessing Executive Functions, Memory, and Social Cognition.

Tsentidou G, Moraitou D, Tsolaki M, Masoura E, Papaliagkas V Diagnostics (Basel). 2022; 12(12).

PMID: 36553024 PMC: 9777412. DOI: 10.3390/diagnostics12123017.


Aging and feature binding in visual working memory.

Holcomb A, Tagliabue C, Mazza V Front Psychol. 2022; 13:977565.

PMID: 36275238 PMC: 9583905. DOI: 10.3389/fpsyg.2022.977565.

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