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Combined Endophthalmitis and Orbital Cellulitis in Patients with Corona Virus Disease (COVID-19)

Overview
Publisher Springer
Specialty Ophthalmology
Date 2021 Sep 15
PMID 34523045
Citations 3
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Abstract

Purpose: To document the presentation of unilateral combined endophthalmitis and orbital cellulitis in patients with COVID-19 infection and study their prognosis.

Patients And Methods: This interventional case series study included 9 patients referred to the Ophthalmology Department, Minia University Hospital with unilateral combined endophthalmitis and orbital cellulitis between April 2020 and March 2021. In addition to the COVID-19 work-up, all patients were subjected to full ophthalmological evaluation and managed according to their ophthalmic and systemic disease.

Results: The patients were 5 females and 4 males. They had clinical, laboratory and imaging findings that confirmed COVID-19 infection. All patients had unilateral endophthalmitis with orbital cellulitis and profound visual loss in the affected eye. Three patients died due to respiratory failure, while 6 patients recovered systemically. The survived patients developed atrophia bulbi in 4 patients and in 2 patients, the globe retained normal size but with complete visual loss.

Conclusion: Combined endophthalmitis and orbital cellulitis can be one of the early presentations of patients with COVID-19 infection with poor visual prognosis.

Trial Registration: Clinical registration: clinicaltrials.gov identifier: NCT04456556 .

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Endogenous panophthalmitis in a patient with COVID-19 during hospitalization in an intensive care unit: A case report.

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How Does SARS-CoV-2 Affect Our Eyes-What Have We Learnt So Far about the Ophthalmic Manifestations of COVID-19?.

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References
1.
Zhou P, Yang X, Wang X, Hu B, Zhang L, Zhang W . A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020; 579(7798):270-273. PMC: 7095418. DOI: 10.1038/s41586-020-2012-7. View

2.
Turbin R, Wawrzusin P, Sakla N, Traba C, Wong K, Mirani N . Orbital cellulitis, sinusitis and intracranial abnormalities in two adolescents with COVID-19. Orbit. 2020; 39(4):305-310. DOI: 10.1080/01676830.2020.1768560. View

3.
Smitha K, Deshmukh A, Manjandavida F, Babu K . Pediatric viral orbital cellulites secondary to H1N1 infection: A case report. Indian J Ophthalmol. 2019; 67(7):1234-1235. PMC: 6611327. DOI: 10.4103/ijo.IJO_1549_18. View

4.
Daruich A, Martin D, Bremond-Gignac D . Ocular manifestation as first sign of Coronavirus Disease 2019 (COVID-19): Interest of telemedicine during the pandemic context. J Fr Ophtalmol. 2020; 43(5):389-391. PMC: 7164841. DOI: 10.1016/j.jfo.2020.04.002. View

5.
Yoshida A, Obata H, Kawashima H . Cytomegalovirus Uveitis with Hypopyon Mimicking Bacterial Endophthalmitis. Case Rep Ophthalmol Med. 2015; 2015:489813. PMC: 4442280. DOI: 10.1155/2015/489813. View