Biomaterials for Orthopaedic Diagnostics and Theranostics

Overview

Journal Curr Opin Biomed Eng

Specialty Biomedical Engineering

Date 2021 Aug 30

PMID 34458652

Citations 4

Authors

Marian A Ackun-Farmmer

Clyde T Overby

Brittany E Haws

Regine Choe

Danielle S W Benoit

Affiliations

Soon will be listed here.

Abstract

Despite widespread use of conventional diagnostic methods in orthopaedic applications, limitations still exist in detection and diagnosing many pathologies especially at early stages when intervention is most critical. The use of biomaterials to develop diagnostics and theranostics, including nanoparticles and scaffolds for systemic or local applications, has significant promise to address these shortcomings and enable successful clinical translation. These developments in both modular and holistic design of diagnostic and theranostic biomaterials may improve patient treatments for myriad orthopaedic applications ranging from cancer to fractures to infection.

Citing Articles

Theranostics: a multifaceted approach utilizing nano-biomaterials.

Yasir M, Mishra R, Tripathi A, Maurya R, Shahi A, Zaki M Discov Nano. 2024; 19(1):35.

PMID: 38407670 PMC: 10897124. DOI: 10.1186/s11671-024-03979-w.

Polymer-Based Hydrogels Applied in Drug Delivery: An Overview.

Thang N, Chien T, Cuong D Gels. 2023; 9(7).

PMID: 37504402 PMC: 10379988. DOI: 10.3390/gels9070523.

Zwitterionic peptides: Tunable next-generation stealth nanoparticle modifications.

Overby C, Park S, Summers A, Benoit D Bioact Mater. 2023; 27:113-124.

PMID: 37006823 PMC: 10063383. DOI: 10.1016/j.bioactmat.2023.03.020.

Biomaterials and Regenerative Medicine in Pain Management.

Gu X, Carroll Turpin M, Romero-Ortega M Curr Pain Headache Rep. 2022; 26(7):533-541.

PMID: 35727489 PMC: 9325847. DOI: 10.1007/s11916-022-01055-5.

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