The Intestinal Microbiota and Anorexia Nervosa: Cause or Consequence of Nutrient Deprivation

Overview

Journal Curr Opin Endocr Metab Res

Specialty Endocrinology

Date 2021 Aug 30

PMID 34458645

Citations 6

Authors

Kylie K Reed

Afrouz Abbaspour

Cynthia M Bulik

Ian M Carroll

Affiliations

Soon will be listed here.

Abstract

The intestinal microbiota is a diverse microbial community that colonizes the gastrointestinal tract of animals. Abnormal changes in intestinal microbiota has been associated with multiple diseases including inflammatory bowel diseases and obesity; however, emerging evidence suggests a role for the gut microbiota in anxiety and depression via the gut-brain axis. As this microbial community is associated with weight dysregulation and host behavior it is not surprising that the intestinal microbiota may have a role to play in anorexia nervosa (AN). In this review we examine recent studies linking the gut microbiota with nutrition, psychopathology, and ultimately AN. We also review potential gut microbiota-based therapies for AN.

Citing Articles

Harnessing precision nutrition to individualize weight restoration in anorexia nervosa.

Rodriguez I, Huckins L, Bulik C, Xu J, Igudesman D J Eat Disord. 2025; 13(1):29.

PMID: 39962541 PMC: 11834214. DOI: 10.1186/s40337-025-01209-x.

Feeding gut microbes to nourish the brain: unravelling the diet-microbiota-gut-brain axis.

Schneider E, ORiordan K, Clarke G, Cryan J Nat Metab. 2024; 6(8):1454-1478.

PMID: 39174768 DOI: 10.1038/s42255-024-01108-6.

Brain and gut microbiota disorders in the psychopathology of anorexia nervosa.

Garcia-Gil M, Ceccarini M, Stoppini F, Cataldi S, Mazzeschi C, Delvecchio E Transl Neurosci. 2023; 13(1):516-526.

PMID: 36660007 PMC: 9824428. DOI: 10.1515/tnsci-2022-0267.

Role of Short-Chain Fatty Acids Produced by Gut Microbiota in Innate Lung Immunity and Pathogenesis of the Heterogeneous Course of Chronic Obstructive Pulmonary Disease.

Kotlyarov S Int J Mol Sci. 2022; 23(9).

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Giel K, Bulik C, Fernandez-Aranda F, Hay P, Keski-Rahkonen A, Schag K Nat Rev Dis Primers. 2022; 8(1):16.

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