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Photoacoustic Computed Tomography for Functional Human Brain Imaging [Invited]

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Specialty Radiology
Date 2021 Aug 30
PMID 34457399
Citations 26
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Abstract

The successes of magnetic resonance imaging and modern optical imaging of human brain function have stimulated the development of complementary modalities that offer molecular specificity, fine spatiotemporal resolution, and sufficient penetration simultaneously. By virtue of its rich optical contrast, acoustic resolution, and imaging depth far beyond the optical transport mean free path (∼1 mm in biological tissues), photoacoustic computed tomography (PACT) offers a promising complementary modality. In this article, PACT for functional human brain imaging is reviewed in its hardware, reconstruction algorithms, demonstration, and potential roadmap.

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