Testicular Torsion and Spermatogenesis

Overview

Journal Adv Exp Med Biol

Specialties Biology
General Medicine

Date 2021 Aug 28

PMID 34453742

Citations 5

Authors

Omar Al Hussein Alawamlh

Ryan Flannigan

Russell Hayden

Marc Goldstein

Philip S Li

Richard K Lee

Affiliations

Soon will be listed here.

Abstract

Testicular torsion (TT) is a common urologic emergency that can occur at any age. It is most common in newborns and during puberty. Prompt evaluation and management is required to salvage the testis following an episode of torsion. TT brings about damage to testicular tissue and spermatogenesis through various hypothesized mechanisms; however there is a consensus that the effects of ischemia, ischemia-reperfusion injury, and oxidative stress account for the most destructive effects. Numerous studies have examined the effects of various agents and therapies in limiting the effects of TT on the testis.

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