» Articles » PMID: 34429981

Rituximab-induced Acute Lympholysis and Pancytopenia After COVID-19 Vaccination

Overview
Journal Clin Case Rep
Date 2021 Aug 25
PMID 34429981
Citations 2
Authors
Affiliations
Soon will be listed here.
Abstract

Rituximab and COVID-19 vaccine can cause massive hyperacute depletion of B cells and plasma cells, as well as subsequent cytokine release syndrome, coagulopathy, and pancytopenia. These effects differ from the adverse effects that have been reported for rituximab, and new guidelines regarding the timing of rituximab infusion and vaccination are urgently needed.

Citing Articles

Therapy in the Course of Kidney Graft Rejection-Implications for the Cardiovascular System-A Systematic Review.

Mizera J, Pilch J, Giordano U, Krajewska M, Banasik M Life (Basel). 2023; 13(7).

PMID: 37511833 PMC: 10381422. DOI: 10.3390/life13071458.


Rituximab-induced acute lympholysis and pancytopenia after COVID-19 vaccination.

Leung V, Lin Y Clin Case Rep. 2021; 9(8):e04517.

PMID: 34429981 PMC: 8365555. DOI: 10.1002/ccr3.4517.

References
1.
Leung V, Lin Y . Rituximab-induced acute lympholysis and pancytopenia after COVID-19 vaccination. Clin Case Rep. 2021; 9(8):e04517. PMC: 8365555. DOI: 10.1002/ccr3.4517. View

2.
Sidner R, Book B, Agarwal A, Bearden C, Vieira C, Pescovitz M . In vivo human B-cell subset recovery after in vivo depletion with rituximab, anti-human CD20 monoclonal antibody. Hum Antibodies. 2004; 13(3):55-62. View

3.
Selewski D, Shah G, Mody R, Rajdev P, Mukherji S . Rituximab (Rituxan). AJNR Am J Neuroradiol. 2010; 31(7):1178-80. PMC: 7965451. DOI: 10.3174/ajnr.A2142. View

4.
Fajgenbaum D, June C . Cytokine Storm. N Engl J Med. 2020; 383(23):2255-2273. PMC: 7727315. DOI: 10.1056/NEJMra2026131. View

5.
Griffin M, Makris M . Vaccination induced neutropenia. Int J Lab Hematol. 2013; 35(5):e33. DOI: 10.1111/ijlh.12063. View