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Induction Strategy for Locally Advanced Thymoma

Overview
Journal Front Oncol
Specialty Oncology
Date 2021 Aug 9
PMID 34367988
Citations 7
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Abstract

Surgery remains cornerstone for the management of thymoma. Complete surgical resection (R0), is recognized as the constant and significant factor for prognosis. However, in locally advanced (Masaoka-Koga stages III-IVa) thymomas, achieving R0 resection remains challenging due to local-regional invasion of the disease. Induction treatment, with the aim of reducing bulky tumor mass, offers new strategy to facilitate totally surgical resection. Herein, we reviewed recent progress and provided a comprehensive overview of induction strategy in locally advance thymoma.

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References
1.
Akaogi E, Ohara K, Mitsui K, Onizuka M, Ishikawa S, Mitsui T . Preoperative radiotherapy and surgery for advanced thymoma with invasion to the great vessels. J Surg Oncol. 1996; 63(1):17-22. DOI: 10.1002/(SICI)1096-9098(199609)63:1<17::AID-JSO4>3.0.CO;2-T. View

2.
Khorfan R, Bharat A, Odell D . Management and Long-Term Outcomes of Advanced Stage Thymoma in the United States. Ann Thorac Surg. 2020; 111(1):223-230. PMC: 8452232. DOI: 10.1016/j.athoracsur.2020.05.088. View

3.
Huang J, Ahmad U, Antonicelli A, Catlin A, Fang W, Gomez D . Development of the international thymic malignancy interest group international database: an unprecedented resource for the study of a rare group of tumors. J Thorac Oncol. 2014; 9(10):1573-8. DOI: 10.1097/JTO.0000000000000269. View

4.
Marchevsky A, Walts A . PD-L1, PD-1, CD4, and CD8 expression in neoplastic and nonneoplastic thymus. Hum Pathol. 2016; 60:16-23. DOI: 10.1016/j.humpath.2016.09.023. View

5.
Fujii Y . Published guidelines for management of thymoma. Thorac Surg Clin. 2010; 21(1):125-9, viii. DOI: 10.1016/j.thorsurg.2010.08.002. View