Maternal, Foetal and Child Consequences of Immunosuppressive Drugs During Pregnancy in Women with Organ Transplant: a Review

Overview

Journal Clin Kidney J

Publisher Oxford University Press

Specialty Nephrology

Date 2021 Aug 4

PMID 34345409

Citations 12

Authors

Hugoline Boulay

Severine Mazaud-Guittot

Jeanne Supervielle

Jonathan M Chemouny

Virginie Dardier

Agnes Lacroix

Ludivine Dion

Cecile Vigneau

Affiliations

Soon will be listed here.

Abstract

Although pregnancy remains exceptional in women after heart, liver or lung transplant, obstetricians and nephrologists are regularly confronted with pregnancy in renal transplant recipients. National and international registries have described the epidemiology of maternal, foetal and neonatal complications, and transplantation societies have published recommendations on the monitoring of these high-risk pregnancies. In this review, we summarize the existing data on maternal and foetal complications of pregnancies in women after renal transplant, especially the management of immunosuppression. We also describe the few available data on the middle- and long-term outcomes of their children who were exposed to immunosuppressive drugs.

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