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Severine Mazaud-Guittot

Explore the profile of Severine Mazaud-Guittot including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 526
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Recent Articles
1.
De Bono C, Xu Y, Kausar S, Herbane M, Humbert C, Rafatov S, et al.
Development . 2025 Feb; 152(5). PMID: 39927812
Forty first-trimester human hearts were studied to lay groundwork for further studies of the mechanisms underlying congenital heart defects. We first sampled 49,227 cardiac nuclei from three fetuses at 8.6,...
2.
Villalba A, Gitton Y, Aiello V, Toupin M, Mazaud-Guittot S, Chedotal A, et al.
Diabetes . 2024 Nov; 74(3):368-375. PMID: 39602451
Article Highlights: Data on human pancreas development are limited and derived from two-dimensional staining. We overcome this using in toto staining, tissue clearing, and light-sheet imaging. We sought to understand...
3.
Svingen T, Andersson A, Angelova J, Axelstad M, Bakker J, Baumann L, et al.
Open Res Eur . 2024 Jun; 4:68. PMID: 38883262
The prevalence of hormone-related health issues caused by exposure to endocrine disrupting chemicals (EDCs) is a significant, and increasing, societal challenge. Declining fertility rates together with rising incidence rates of...
4.
Vazakidou P, Evangelista S, Li T, Lecante L, Rosenberg K, Koekkoek J, et al.
Reprod Biol Endocrinol . 2024 May; 22(1):60. PMID: 38778396
Background: Reproduction in women is at risk due to exposure to chemicals that can disrupt the endocrine system during different windows of sensitivity throughout life. Steroid hormone levels are fundamental...
5.
Villalba A, Gitton Y, Inoue M, Aiello V, Blain R, Toupin M, et al.
Diabetologia . 2024 Apr; 67(6):1066-1078. PMID: 38630142
Aims/hypothesis: Rodent pancreas development has been described in great detail. On the other hand, there are still gaps in our understanding of the developmental trajectories of pancreatic cells during human...
6.
Blain R, Couly G, Shotar E, Blevinal J, Toupin M, Favre A, et al.
Cell . 2023 Dec; 186(26):5910-5924.e17. PMID: 38070509
The evolution and development of the head have long captivated researchers due to the crucial role of the head as the gateway for sensory stimuli and the intricate structural complexity...
7.
Lesne L, Desdoits-Lethimonier C, Hug E, Costet N, Raffenne L, Toupin M, et al.
Toxicol Sci . 2023 Jul; 195(2):169-183. PMID: 37505509
Valproic acid (VPA) has long been the most widely used antiepileptic drug (AED) for the treatment of epilepsy, bipolar psychiatric disorders, and migraine. However, long-term VPA treatment has several adverse...
8.
Mary L, Leclerc D, Labalme A, Bellaud P, Mazaud-Guittot S, Dreano S, et al.
Genes (Basel) . 2023 Feb; 14(2). PMID: 36833200
Sexual development is a complex process relying on numerous genes. Disruptions in some of these genes are known to cause differences of sexual development (DSDs). Advances in genome sequencing allowed...
9.
Kugathas I, Johansson H, Chan Sock Peng E, Toupin M, Evrard B, Darde T, et al.
Arch Toxicol . 2023 Jan; 97(3):849-863. PMID: 36653537
Exposure to endocrine-disrupting chemicals (EDCs) during development may cause reproductive disorders in women. Although female reproductive endpoints are assessed in rodent toxicity studies, a concern is that typical endpoints are...
10.
Pinsard M, Mouchet N, Dion L, Bessede T, Bertrand M, Darai E, et al.
Fertil Steril . 2022 Apr; 117(6):1279-1288. PMID: 35367063
Objective: To better understand the physiology of pain in pelvic pain pathological conditions, such as endometriosis, in which alterations of uterine innervation have been highlighted, we performed an anatomic and...