Bifidobacterium Longum: Protection Against Inflammatory Bowel Disease

Overview

Journal J Immunol Res

Publisher Wiley

Specialty Allergy & Immunology

Date 2021 Aug 2

PMID 34337079

Citations 70

Authors

Shunyu Yao

Zixi Zhao

Weijun Wang

Xiaolu Liu

Affiliations

Soon will be listed here.

Abstract

The prevalence of inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn's disease (CD), increases gradually worldwide in the past decades. IBD is generally associated with the change of the immune system and gut microbiota, and the conventional treatments usually result in some side effects. Bifidobacterium longum, as colonizing bacteria in the intestine, has been demonstrated to be capable of relieving colitis in mice and can be employed as an alternative or auxiliary way for treating IBD. Here, the mechanisms of the Bifidobacterium longum in the treatment of IBD were summarized based on previous cell and animal studies and clinical trials testing bacterial therapies. This review will be served as a basis for future research on IBD treatment.

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