Medullary Carcinoma of the Colon: A Histopathologic Challenge

Overview

Journal Cureus

Specialty Biomedical Engineering

Date 2021 Jul 30

PMID 34327072

Citations 3

Authors

Zainab Fatima

Purva Sharma

Bahaaeldin Youssef

Koyamangalath Krishnan

Affiliations

Soon will be listed here.

Abstract

Medullary carcinoma (MC) of the colon is a rare and unique histologic subtype of colorectal cancer. It is commonly associated with deficient mismatch repair proteins and has a strong association with Lynch syndrome. Diagnosis is challenging as it does not have the usual immunohistochemical stains on pathology seen in colorectal adenocarcinoma. Here, we discuss an interesting case of MC of the colon that was metastatic on presentation and constituted a diagnostic challenge.

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