Interaction Between Sex-determining Genes from Two Species: Clues from Hybrids

Overview

Journal Philos Trans R Soc Lond B Biol Sci

Specialty Biology

Date 2021 Jul 26

PMID 34304589

Citations 3

Authors

Alvaro S Roco

Adrian Ruiz-Garcia

Monica Bullejos

Affiliations

Soon will be listed here.

Abstract

Hybrids provide an interesting model to study the evolution of sex-determining genes and sex chromosome systems as they offer the opportunity to see how independently evolving sex-determining pathways interact . In this context, the genus represents a stimulating model, since species with non-homologous sex chromosomes and different sex-determining genes have been identified. In addition, the possibility of interspecies breeding is favoured in this group, which arose by alloploidization events, with species ploidy ranging from 2 = 2 = 20 in (the only diploid representative of the genus) to 2 = 12 = 108 in . To study how two sex-determining genes interact , × s hybrids were produced. Gonadal differentiation in these hybrids revealed that the gene is dominant over male-determining sex chromosomes (Y or Z), even though the Y chromosome is dominant in (Y > W>Z). In the absence of the gene (the Z chromosome from is present), the W chromosome from is able to trigger ovarian development. Testicular differentiation will take place in the absence of W chromosomes from any of the parental species. The dominance/recessivity relationships between these sex-determining loci in the context of either parental genome remains unknown. This article is part of the theme issue 'Challenging the paradigm in sex chromosome evolution: empirical and theoretical insights with a focus on vertebrates (Part II)'.

Citing Articles

Expanding the classical paradigm: what we have learnt from vertebrates about sex chromosome evolution.

Kratochvil L, Stock M, Rovatsos M, Bullejos M, Herpin A, Jeffries D Philos Trans R Soc Lond B Biol Sci. 2021; 376(1833):20200097.

PMID: 34304593 PMC: 8310716. DOI: 10.1098/rstb.2020.0097.

Preface.

Kratochvil L, Stock M Philos Trans R Soc Lond B Biol Sci. 2021; 376(1832):20200088.

PMID: 34247506 PMC: 8273501. DOI: 10.1098/rstb.2020.0088.

Testis Development and Differentiation in Amphibians.

Roco A, Ruiz-Garcia A, Bullejos M Genes (Basel). 2021; 12(4).

PMID: 33923451 PMC: 8072878. DOI: 10.3390/genes12040578.

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