Artificial Intelligence in Healthcare: Transforming the Practice of Medicine

Overview

Journal Future Healthc J

Specialty Health Services

Date 2021 Jul 21

PMID 34286183

Citations 149

Authors

Junaid Bajwa

Usman Munir

Aditya Nori

Bryan Williams

Affiliations

Soon will be listed here.

Abstract

Artificial intelligence (AI) is a powerful and disruptive area of computer science, with the potential to fundamentally transform the practice of medicine and the delivery of healthcare. In this review article, we outline recent breakthroughs in the application of AI in healthcare, describe a roadmap to building effective, reliable and safe AI systems, and discuss the possible future direction of AI augmented healthcare systems.

Citing Articles

The Value of Clinical Decision Support in Healthcare: A Focus on Screening and Early Detection.

Schafer H, Lajmi N, Valente P, Pedrioli A, Cigoianu D, Hoehne B Diagnostics (Basel). 2025; 15(5).

PMID: 40075895 PMC: 11899545. DOI: 10.3390/diagnostics15050648.

Advancements in the application of artificial intelligence in the field of colorectal cancer.

Zhu M, Zhai Z, Wang Y, Chen F, Liu R, Yang X Front Oncol. 2025; 15:1499223.

PMID: 40071094 PMC: 11893421. DOI: 10.3389/fonc.2025.1499223.

Leveraging a hybrid convolutional gated recursive diabetes prediction and severity grading model through a mobile app.

Alsayed A, Ismail N, Hasan L, Binsawad M, Embarak F PeerJ Comput Sci. 2025; 11:e2642.

PMID: 40062236 PMC: 11888868. DOI: 10.7717/peerj-cs.2642.

Analysing the Suitability of Artificial Intelligence in Healthcare and the Role of AI Governance.

You Z, Wang Y, Xiao Y Health Care Anal. 2025; .

PMID: 40048068 DOI: 10.1007/s10728-025-00514-5.

Assessing the performance of large language models (GPT-3.5 and GPT-4) and accurate clinical information for pediatric nephrology.

Sav N Pediatr Nephrol. 2025; .

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References

Gulshan V, Peng L, Coram M, Stumpe M, Wu D, Narayanaswamy A . Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs. JAMA. 2016; 316(22):2402-2410. DOI: 10.1001/jama.2016.17216. View

Lasko T, Denny J, Levy M . Computational phenotype discovery using unsupervised feature learning over noisy, sparse, and irregular clinical data. PLoS One. 2013; 8(6):e66341. PMC: 3691199. DOI: 10.1371/journal.pone.0066341. View

Senior A, Evans R, Jumper J, Kirkpatrick J, Sifre L, Green T . Improved protein structure prediction using potentials from deep learning. Nature. 2020; 577(7792):706-710. DOI: 10.1038/s41586-019-1923-7. View

Nachev P, Herron D, McNally N, Rees G, Williams B . Redefining the research hospital. NPJ Digit Med. 2019; 2:119. PMC: 6897858. DOI: 10.1038/s41746-019-0201-2. View

Topol E . High-performance medicine: the convergence of human and artificial intelligence. Nat Med. 2019; 25(1):44-56. DOI: 10.1038/s41591-018-0300-7. View

Esteva A, Robicquet A, Ramsundar B, Kuleshov V, DePristo M, Chou K . A guide to deep learning in healthcare. Nat Med. 2019; 25(1):24-29. DOI: 10.1038/s41591-018-0316-z. View

Bodenheimer T, Sinsky C . From triple to quadruple aim: care of the patient requires care of the provider. Ann Fam Med. 2014; 12(6):573-6. PMC: 4226781. DOI: 10.1370/afm.1713. View

Quinn T, Senadeera M, Jacobs S, Coghlan S, Le V . Trust and medical AI: the challenges we face and the expertise needed to overcome them. J Am Med Inform Assoc. 2020; 28(4):890-894. PMC: 7973477. DOI: 10.1093/jamia/ocaa268. View

Haque A, Milstein A, Fei-Fei L . Illuminating the dark spaces of healthcare with ambient intelligence. Nature. 2020; 585(7824):193-202. DOI: 10.1038/s41586-020-2669-y. View

10.

Xie Y, Nguyen Q, Hamzah H, Lim G, Bellemo V, Gunasekeran D . Artificial intelligence for teleophthalmology-based diabetic retinopathy screening in a national programme: an economic analysis modelling study. Lancet Digit Health. 2020; 2(5):e240-e249. DOI: 10.1016/S2589-7500(20)30060-1. View

11.

LeCun Y, Bengio Y, Hinton G . Deep learning. Nature. 2015; 521(7553):436-44. DOI: 10.1038/nature14539. View

12.

Wang A, Nguyen D, Sridhar A, Gollakota S . Using smart speakers to contactlessly monitor heart rhythms. Commun Biol. 2021; 4(1):319. PMC: 7943557. DOI: 10.1038/s42003-021-01824-9. View

13.

Muehlematter U, Daniore P, Vokinger K . Approval of artificial intelligence and machine learning-based medical devices in the USA and Europe (2015-20): a comparative analysis. Lancet Digit Health. 2021; 3(3):e195-e203. DOI: 10.1016/S2589-7500(20)30292-2. View

14.

Bellemo V, Lim Z, Lim G, Nguyen Q, Xie Y, Yip M . Artificial intelligence using deep learning to screen for referable and vision-threatening diabetic retinopathy in Africa: a clinical validation study. Lancet Digit Health. 2020; 1(1):e35-e44. DOI: 10.1016/S2589-7500(19)30004-4. View

15.

Oktay O, Nanavati J, Schwaighofer A, Carter D, Bristow M, Tanno R . Evaluation of Deep Learning to Augment Image-Guided Radiotherapy for Head and Neck and Prostate Cancers. JAMA Netw Open. 2020; 3(11):e2027426. PMC: 7705593. DOI: 10.1001/jamanetworkopen.2020.27426. View

16.

Panch T, Mattie H, Celi L . The "inconvenient truth" about AI in healthcare. NPJ Digit Med. 2019; 2:77. PMC: 6697674. DOI: 10.1038/s41746-019-0155-4. View

17.

Bejnordi B, Veta M, van Diest P, van Ginneken B, Karssemeijer N, Litjens G . Diagnostic Assessment of Deep Learning Algorithms for Detection of Lymph Node Metastases in Women With Breast Cancer. JAMA. 2017; 318(22):2199-2210. PMC: 5820737. DOI: 10.1001/jama.2017.14585. View

18.

Reardon S . Rise of Robot Radiologists. Nature. 2019; 576(7787):S54-S58. DOI: 10.1038/d41586-019-03847-z. View

19.

Raumviboonsuk P, Krause J, Chotcomwongse P, Sayres R, Raman R, Widner K . Deep learning versus human graders for classifying diabetic retinopathy severity in a nationwide screening program. NPJ Digit Med. 2019; 2:25. PMC: 6550283. DOI: 10.1038/s41746-019-0099-8. View

20.

Kelly C, Karthikesalingam A, Suleyman M, Corrado G, King D . Key challenges for delivering clinical impact with artificial intelligence. BMC Med. 2019; 17(1):195. PMC: 6821018. DOI: 10.1186/s12916-019-1426-2. View