Panton-valentine Leukocidin Staphylococcus Aureus Severe Infection in an Infant: a Case Report and a Review of the Literature

Overview

Journal Ital J Pediatr

Publisher Biomed Central

Specialty Pediatrics

Date 2021 Jul 18

PMID 34274022

Citations 4

Authors

Massimo Luca Castellazzi

Samantha Bosis

Irene Borzani

Claudia Tagliabue

Raffaella Pinzani

Paola Marchisio

Giada Maria Di Pietro

Affiliations

Soon will be listed here.

Abstract

Background: Panton-Valentine leukocidin (PVL) is one of the major virulence factor of Staphylococcus aureus (SA) that might be associated with invasive life-threating infections. A prompt diagnosis and adequate treatment are essential in achieving the best outcome and avoiding serious sequelae. We describe a case of severe invasive PVL-SA infection in an infant. A literature review starting from 2010 was also performed in order to discuss clinical presentations, radiological findings, treatment and outcome.

Case Presentation: This is a case of a 6-month-old boy who rapidly developed high fever and poor general condition. He was diagnosed as having multiple muscular abscesses, multiple foci of osteomyelitis and bloodstream infections caused by Panton-Valentine leukocidin Methicillin-resistant Staphylococcus aureus. He received intravenous antibiotics and surgical drainage of the abscess with progressive recovery.

Conclusion: Our report highlights the importance of improving awareness of this severe infection, as a prompt diagnosis and adequate manage is essential in order to save life and to prevent serious complications.

Citing Articles

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