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Bacteremia in a Centenarian and Pathogen Traceability: A Case Report

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Specialty General Medicine
Date 2021 Jul 5
PMID 34222461
Citations 1
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Abstract

Background: Early diagnosis and appropriate antibiotic treatment are important to survival of () bacteremia. Penicillin tends to be the most commonly used antibiotic. However, there are limited data on antibiotic use in elderly patients with serious complications. We describe the clinical presentation, antibiotic therapy, and traceability of in a centenarian with a history of eating frozen food.

Case Summary: A 102-year-old man suffered from high fever with chill after hematochezia. Tentative diagnoses were lower gastrointestinal hemorrhage and localized peritonitis. Meropenem and ornidazole were the empirical therapy. The patient did not respond and developed multiple system dysfunction even after teicoplanin was added to the therapy. was identified from blood cultures on day 5 of admission. The patient had a history of consuming frozen dumplings. Meropenem/ornidazole/teicoplanin were replaced with meropenem/linezolid. The patient gradually became afebrile. He received meropenem/linezolid for 10 d, and piperacillin/tazobactam was applied as step-down treatment for 2 wk with good clinical results. There was no sign of relapse during follow-up after discharge. isolates from the patient and frozen dumplings belonged to different serotypes and sequence types (STs): 1/2b and ST5 from the patient and 1/2c and ST9 from the dumplings.

Conclusion: More awareness of listeriosis should be raised. Linezolid might be an option for listeriosis in elderly people with serious complications.

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References
1.
Singer M, Deutschman C, Seymour C, Shankar-Hari M, Annane D, Bauer M . The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016; 315(8):801-10. PMC: 4968574. DOI: 10.1001/jama.2016.0287. View

2.
Mariscotti J, Quereda J, Garcia-Del Portillo F, Pucciarelli M . The Listeria monocytogenes LPXTG surface protein Lmo1413 is an invasin with capacity to bind mucin. Int J Med Microbiol. 2014; 304(3-4):393-404. DOI: 10.1016/j.ijmm.2014.01.003. View

3.
Zhang X, Niu Y, Liu Y, Lu Z, Wang D, Cui X . Isolation and Characterization of Clinical in Beijing, China, 2014-2016. Front Microbiol. 2019; 10:981. PMC: 6517826. DOI: 10.3389/fmicb.2019.00981. View

4.
Stepanovic S, Lazarevic G, Jesic M, KOS R . Meropenem therapy failure in Listeria monocytogenes infection. Eur J Clin Microbiol Infect Dis. 2004; 23(6):484-6. DOI: 10.1007/s10096-004-1135-3. View

5.
Maertens de Noordhout C, Devleesschauwer B, Angulo F, Verbeke G, Haagsma J, Kirk M . The global burden of listeriosis: a systematic review and meta-analysis. Lancet Infect Dis. 2014; 14(11):1073-1082. PMC: 4369580. DOI: 10.1016/S1473-3099(14)70870-9. View