Lung Cancer Screening: Who Pays? Who Receives?-the Chinese Perspective
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The National Lung Screening Trial (NLST) revealed that low-dose computed tomography (LDCT) screening reduced lung cancer mortality by 20.0%. In China, LDCT is very cheap and easy to access. As a result, LDCT screening is not limited to "high-risk" population defined by the NLST trial. The results of LDCT screening in China are also quite different from that in Western countries. LDCT detected lung cancer in a significant proportion of young, female and non-smokers in China. There is also a higher proportion of adenocarcinoma (ADC), a lower proportion of squamous cell carcinoma, and a higher proportion of early-stage 0/I disease among LDCT-detected lung cancer in China. The issue of overdiagnosis and overtreatment is discussed. Finally, we call the global attention to clarify the etiology of lung cancer in young female non-smokers.
Cost-effectiveness of lung cancer screening by low-dose CT in China: a micro-simulation study.
Du Y, Li Y, Sidorenkov G, Vliegenthart R, Heuvelmans M, Dorrius M J Natl Cancer Cent. 2024; 2(1):18-24.
PMID: 39035210 PMC: 11256619. DOI: 10.1016/j.jncc.2021.11.002.
Zhou Y, Xiang Z, Lin W, Lin J, Wen Y, Wu L BMC Pulm Med. 2024; 24(1):25.
PMID: 38200537 PMC: 10782768. DOI: 10.1186/s12890-024-02841-0.
Zheng Y, Dong J, Yang X, Shuai P, Li Y, Li H Cancer Med. 2023; 12(11):12050-12064.
PMID: 37248730 PMC: 10278478. DOI: 10.1002/cam4.5886.
Bidzinska J, Szurowska E Cancers (Basel). 2023; 15(4).
PMID: 36831662 PMC: 9954317. DOI: 10.3390/cancers15041321.
Almatrafi A, Thomas O, Callister M, Gabe R, Beeken R, Neal R J Med Screen. 2022; 30(1):3-13.
PMID: 35942779 PMC: 9925896. DOI: 10.1177/09691413221117685.