Maternal Pregnancy Diet, Postnatal Home Environment and Executive Function and Behavior in 3- to 4-y-olds

Overview

Journal Am J Clin Nutr

Publisher Elsevier

Specialty Nutritional Sciences

Date 2021 Jun 23

PMID 34159358

Citations 5

Authors

Neda Mortaji

John E Krzeczkowski

Khrista Boylan

Linda Booij

Maude Perreault

Ryan J Van Lieshout

Affiliations

Soon will be listed here.

Abstract

Background: Optimal maternal nutrition during pregnancy has been linked to better cognitive and behavioral development in children. However, its influence on the effects of suboptimal postnatal exposures like reduced stimulation and support in the home is not known.

Objectives: To examine the effect of maternal pregnancy diet on executive function and/or behavioral development in children raised in suboptimal home environments.

Methods: Data were provided by 808 mother-infant dyads from the Canadian Maternal-Infant Research on Environmental Chemicals-Child Development study. Maternal pregnancy diet was self-reported using the Healthy Eating Index 2010 questionnaire. Stimulation and support in the home was assessed using the Home Observation for Measurement of the Environment (HOME) when children were 3-4 y old. Child executive function was reported by mothers at this age using the Behavior Rating Inventory of Executive Functioning-Preschool Edition, and child behavior was assessed using the Behavior Assessment System for Children-2nd Edition. We examined the interaction of maternal pregnancy diet and postnatal HOME scores on child executive function and behavior using linear regression adjusted for maternal education, postpartum depression, prepregnancy BMI, and smoking.

Results: Maternal pregnancy diet was associated with an increasingly positive association with child working memory (β: 0.21; 95% CI: 0.82, 3.41; P = 0.001), planning (β: 0.17; 95% CI: 0.38, 2.84; P = 0.007), and adaptability (β: -0.13; 95% CI: -1.72, -0.08; P = 0.032) as levels of postnatal stimulation decreased.

Conclusions: The positive association of maternal pregnancy diet quality and executive function and adaptability in 3- to 4-y-olds appeared to increase with decreasing levels of postnatal stimulation and support. These results suggest that overall maternal pregnancy diet could be linked to better child neurodevelopment in families experiencing barriers to providing stimulation and support to children in their home.

Citing Articles

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References

Guenther P, Kirkpatrick S, Reedy J, Krebs-Smith S, Buckman D, Dodd K . The Healthy Eating Index-2010 is a valid and reliable measure of diet quality according to the 2010 Dietary Guidelines for Americans. J Nutr. 2014; 144(3):399-407. PMC: 3927552. DOI: 10.3945/jn.113.183079. View

Holth Skogan A, Zeiner P, Egeland J, Urnes A, Reichborn-Kjennerud T, Aase H . Parent ratings of executive function in young preschool children with symptoms of attention-deficit/-hyperactivity disorder. Behav Brain Funct. 2015; 11:16. PMC: 4399220. DOI: 10.1186/s12993-015-0060-1. View

Thomas Rajarethnem H, Bhat K, Jc M, Kumar Gopalkrishnan S, Mugundhu Gopalram R, Rai K . Combined Supplementation of Choline and Docosahexaenoic Acid during Pregnancy Enhances Neurodevelopment of Fetal Hippocampus. Neurol Res Int. 2017; 2017:8748706. PMC: 5292192. DOI: 10.1155/2017/8748706. View

Maslowski A, Abbas H, Abrams K, Taraman S, Garberson F, Segar S . Project Rosetta: a childhood social, emotional, and behavioral developmental feature mapping. J Biomed Semantics. 2021; 12(1):8. PMC: 8051063. DOI: 10.1186/s13326-021-00242-4. View

Klein E, Ruiz C, Morales K, Stanley P . Variations in Parent and Teacher Ratings of Internalizing, Externalizing, Adaptive Skills, and Behavioral Symptoms in Children with Selective Mutism. Int J Environ Res Public Health. 2019; 16(21). PMC: 6862511. DOI: 10.3390/ijerph16214070. View

Totsika V, Sylva K . The Home Observation for Measurement of the Environment Revisited. Child Adolesc Ment Health. 2020; 9(1):25-35. DOI: 10.1046/j.1475-357X.2003.00073.x. View

Cordner Z, Khambadkone S, Boersma G, Song L, Summers T, Moran T . Maternal high-fat diet results in cognitive impairment and hippocampal gene expression changes in rat offspring. Exp Neurol. 2019; 318:92-100. PMC: 6588424. DOI: 10.1016/j.expneurol.2019.04.018. View

Van den Bergh B . Developmental programming of early brain and behaviour development and mental health: a conceptual framework. Dev Med Child Neurol. 2011; 53 Suppl 4:19-23. DOI: 10.1111/j.1469-8749.2011.04057.x. View

Jin J, Maren S . Prefrontal-Hippocampal Interactions in Memory and Emotion. Front Syst Neurosci. 2015; 9:170. PMC: 4678200. DOI: 10.3389/fnsys.2015.00170. View

10.

Ip P, Ho F, Rao N, Sun J, Young M, Chow C . Impact of nutritional supplements on cognitive development of children in developing countries: A meta-analysis. Sci Rep. 2017; 7(1):10611. PMC: 5587553. DOI: 10.1038/s41598-017-11023-4. View

11.

Simko M, Totka A, Vondrova D, Samohyl M, Jurkovicova J, Trnka M . Maternal Body Mass Index and Gestational Weight Gain and Their Association with Pregnancy Complications and Perinatal Conditions. Int J Environ Res Public Health. 2019; 16(10). PMC: 6572546. DOI: 10.3390/ijerph16101751. View

12.

Snyder H, Miyake A, Hankin B . Advancing understanding of executive function impairments and psychopathology: bridging the gap between clinical and cognitive approaches. Front Psychol. 2015; 6:328. PMC: 4374537. DOI: 10.3389/fpsyg.2015.00328. View

13.

Zhu Y, Gao H, Tong L, Li Z, Wang L, Zhang C . Emotion Regulation of Hippocampus Using Real-Time fMRI Neurofeedback in Healthy Human. Front Hum Neurosci. 2019; 13:242. PMC: 6660260. DOI: 10.3389/fnhum.2019.00242. View

14.

Dos Santos L, Neves Dos Santos D, Bastos A, Assis A, Prado M, Barreto M . Determinants of early cognitive development: hierarchical analysis of a longitudinal study. Cad Saude Publica. 2008; 24(2):427-37. DOI: 10.1590/s0102-311x2008000200022. View

15.

Sandoval-Salazar C, Ramirez-Emiliano J, Trejo-Bahena A, Oviedo-Solis C, Solis-Ortiz M . A high-fat diet decreases GABA concentration in the frontal cortex and hippocampus of rats. Biol Res. 2016; 49:15. PMC: 4772645. DOI: 10.1186/s40659-016-0075-6. View

16.

Knopik V . Maternal smoking during pregnancy and child outcomes: real or spurious effect?. Dev Neuropsychol. 2009; 34(1):1-36. PMC: 3581055. DOI: 10.1080/87565640802564366. View

17.

Nyaradi A, Li J, Hickling S, Foster J, Oddy W . The role of nutrition in children's neurocognitive development, from pregnancy through childhood. Front Hum Neurosci. 2013; 7:97. PMC: 3607807. DOI: 10.3389/fnhum.2013.00097. View

18.

Nomura Y, Marks D, Grossman B, Yoon M, Loudon H, Stone J . Exposure to gestational diabetes mellitus and low socioeconomic status: effects on neurocognitive development and risk of attention-deficit/hyperactivity disorder in offspring. Arch Pediatr Adolesc Med. 2012; 166(4):337-43. PMC: 5959273. DOI: 10.1001/archpediatrics.2011.784. View

19.

Chen X, Zhao D, Mao X, Xia Y, Baker P, Zhang H . Maternal Dietary Patterns and Pregnancy Outcome. Nutrients. 2016; 8(6). PMC: 4924192. DOI: 10.3390/nu8060351. View

20.

Rubin R, Watson P, Duff M, Cohen N . The role of the hippocampus in flexible cognition and social behavior. Front Hum Neurosci. 2014; 8:742. PMC: 4179699. DOI: 10.3389/fnhum.2014.00742. View