Novel Imaging Methods Reveal Positive Impact of Topical Negative Pressure Application on Tissue Perfusion in an in Vivo Skin Model

Overview

Journal Int Wound J

Specialties Emergency Medicine
Orthopedics

Date 2021 Jun 15

PMID 34128314

Citations 12

Authors

Wibke Muller-Seubert

Sascha Roth

Theresa Hauck

Andreas Arkudas

Raymund E Horch

Ingo Ludolph

Affiliations

Soon will be listed here.

Abstract

The influence of topical negative pressure application (TNPA) on tissue perfusion still remains controversial. TNPA was applied for 30 minutes on intact skin of 21 healthy participants. Measurements of tissue oxygen saturation and tissue temperature as signs of tissue perfusion were performed before application of the TNPA, directly after removal of the TNPA and 5, 10, 15, 20, and 30 minutes after removal of the dressing using the near infrared imaging (NIRI) and a thermal imaging camera. Tissue oxygen saturation showed an increase from 67.7% before applying the TNPA to 76.1% directly after removal of TNPA, followed by a decrease of oxygen saturation 30 minutes after removal of TNPA. The measured temperature of the treated skin area increased from 32.1°C to 36.1°C after removal of TNPA with a consecutive decrease of the temperature 30 minutes after removal. TNPA resulted in both a higher tissue oxygen saturation and a higher skin temperature after 30 minutes compared to the beginning. TNPA increases both tissue oxygen saturation and skin temperature as sign of an increase of tissue perfusion. NIRI and thermal imaging proved to be useful for measuring changes in tissue perfusion.

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