» Articles » PMID: 34127980

2020 SARS-CoV-2 Diversification in the United States: Establishing a Pre-vaccination Baseline

Overview
Journal medRxiv
Date 2021 Jun 15
PMID 34127980
Authors
Affiliations
Soon will be listed here.
Abstract

One Sentence Summary: SARS-CoV-2 genetic diversity in the U.S. increased 3-fold in 2020 and 54 emergent nonsynonymous mutations were detected.

References
1.
Ladner J, Larsen B, Bowers J, Hepp C, Bolyen E, Folkerts M . An Early Pandemic Analysis of SARS-CoV-2 Population Structure and Dynamics in Arizona. mBio. 2020; 11(5). PMC: 7474171. DOI: 10.1128/mBio.02107-20. View

2.
Starr T, Greaney A, Addetia A, Hannon W, Choudhary M, Dingens A . Prospective mapping of viral mutations that escape antibodies used to treat COVID-19. Science. 2021; 371(6531):850-854. PMC: 7963219. DOI: 10.1126/science.abf9302. View

3.
Worobey M, Pekar J, Larsen B, Nelson M, Hill V, Joy J . The emergence of SARS-CoV-2 in Europe and North America. Science. 2020; 370(6516):564-570. PMC: 7810038. DOI: 10.1126/science.abc8169. View

4.
Zhang W, Davis B, Chen S, Sincuir Martinez J, Plummer J, Vail E . Emergence of a Novel SARS-CoV-2 Variant in Southern California. JAMA. 2021; 325(13):1324-1326. PMC: 7879386. DOI: 10.1001/jama.2021.1612. View

5.
Shen X, Tang H, McDanal C, Wagh K, Fischer W, Theiler J . SARS-CoV-2 variant B.1.1.7 is susceptible to neutralizing antibodies elicited by ancestral spike vaccines. Cell Host Microbe. 2021; 29(4):529-539.e3. PMC: 7934674. DOI: 10.1016/j.chom.2021.03.002. View