Advances in Biological Function and Clinical Application of Small Extracellular Vesicle Membrane Proteins

Overview

Journal Front Oncol

Specialty Oncology

Date 2021 Jun 7

PMID 34094979

Citations 16

Authors

Defa Huang

Jie Chen

Die Hu

Fangfang Xie

Tong Yang

Zhengzhe Li

Xiaoxing Wang

Yongwei Xiao

Jianing Zhong

Yu Jiang

Xiaokang Zhang

Tianyu Zhong

Affiliations

Soon will be listed here.

Abstract

Small extracellular vesicles are membrane-bound vesicles secreted into extracellular spaces by virtually all types of cells. These carry a large number of membrane proteins on their surface that are incorporated during their biogenesis in cells. The composition of the membrane proteins hence bears the signature of the cells from which they originate. Recent studies have suggested that the proteins on these small extracellular vesicles can serve as biomarkers and target proteins for the diagnosis and treatment of diseases. This article classifies small extracellular vesicle membrane proteins and summarizes their pathophysiological functions in the diagnosis and treatment of diseases.

Citing Articles

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Research progress on the role of extracellular vesicles in neurodegenerative diseases.

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Role of microRNA carried by small extracellular vesicles in urological tumors.

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